1 型糖尿病孕妇的糖尿病技术--分布情况及其对血糖调节和围产期结果的影响

Sara Yalda Ghaur, Pernille Bundgaard Grinderslev, Magnus Leth-Møller, P. G. Ovesen, J. Fuglsang, Sanne Fisker, H. D. McIntyre, Ulla Kampmann
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引用次数: 0

摘要

妊娠合并 1 型糖尿病(TID)会增加产科和新生儿不良后果的风险。妊娠前和整个孕期的最佳血糖控制对于减少并发症至关重要。糖尿病技术的使用正在迅速增加。本研究旨在调查 1 型糖尿病孕妇使用糖尿病技术的情况及其影响。研究人员进行了一项回顾性队列研究;84 名妇女被纳入分析范围,并根据她们的血糖监测方法和胰岛素注射方法被分为不同的亚组。所有亚组的 HbA1c 值在孕期均有所下降,各亚组间无明显差异。不过,在出生体重 Z 值方面发现了差异。与未使用传感器和胰岛素泵的妇女相比,使用传感器和胰岛素泵的妇女所生的婴儿较大。研究结果表明,糖尿病技术,包括胰岛素泵和/或血糖传感器,并不比自我监测血糖测量和每日多次注射胰岛素疗法更有优势。
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Diabetes Technology in Pregnant Women with Type 1 Diabetes—Distribution and Effects on Glycemic Regulation and Perinatal Outcomes
Pregnancies complicated by type 1 diabetes (TID) are associated with an increased risk of obstetric and neonatal adverse outcomes. Optimal glycemic control prior to and through pregnancy is crucial to reduce complications. The use of diabetes technology is rapidly increasing. The aim of the study was to investigate the use and effects of diabetes technology in pregnant women with type 1 diabetes. A retrospective cohort study was conducted; 84 women were included in the analysis and were divided into subgroups according to their glucose monitoring method and insulin delivery method. HbA1c values declined during pregnancy in all subgroups with no significant difference between the subgroups. A difference was, however, found in birth weight z-scores. Women using a sensor and an insulin pump had larger babies compared to women without these treatment modalities. The results of the study indicate that diabetes technology, including insulin pumps and/or glucose sensors are not superior to self-monitoring blood glucose measurement and multiple daily injection insulin therapy, which is comforting in the light of the unequal access to health benefits.
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