{"title":"幻觉与记忆：阿尔茨海默氏症患者的幻觉与自传体过度泛化之间的关系。","authors":"Mohamad El Haj, Frank Larøi","doi":"10.1017/neu.2024.7","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Alzheimer's disease (AD) has been associated with autobiographical overgenerality (i.e. a tendency of patients to retrieve general rather than specific personal memories). AD has also been associated with hallucinations. We investigated the relationship between autobiographical overgenerality and hallucinations in AD.</p><p><strong>Methods: </strong>We invited 28 patients with mild AD to retrieve autobiographical memories, and we also evaluated the occurrence of hallucinations in these patients.</p><p><strong>Results: </strong>Analysis demonstrated significant correlations between hallucinations and autobiographical overgenerality in the patients.</p><p><strong>Conclusion: </strong>AD patients who are distressed by hallucinations may demonstrate autobiographical overgenerality as a strategy to avoid retrieving distressing information that may be related with hallucinations. However, hallucinations as observed in our study can be attributed to other factors such as the general cognitive decline in AD.</p>","PeriodicalId":48964,"journal":{"name":"Acta Neuropsychiatrica","volume":null,"pages":null},"PeriodicalIF":2.6000,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"On hallucinations and memory: the relationship between hallucinations and autobiographical overgenerality in Alzheimer's Disease.\",\"authors\":\"Mohamad El Haj, Frank Larøi\",\"doi\":\"10.1017/neu.2024.7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Alzheimer's disease (AD) has been associated with autobiographical overgenerality (i.e. a tendency of patients to retrieve general rather than specific personal memories). AD has also been associated with hallucinations. We investigated the relationship between autobiographical overgenerality and hallucinations in AD.</p><p><strong>Methods: </strong>We invited 28 patients with mild AD to retrieve autobiographical memories, and we also evaluated the occurrence of hallucinations in these patients.</p><p><strong>Results: </strong>Analysis demonstrated significant correlations between hallucinations and autobiographical overgenerality in the patients.</p><p><strong>Conclusion: </strong>AD patients who are distressed by hallucinations may demonstrate autobiographical overgenerality as a strategy to avoid retrieving distressing information that may be related with hallucinations. However, hallucinations as observed in our study can be attributed to other factors such as the general cognitive decline in AD.</p>\",\"PeriodicalId\":48964,\"journal\":{\"name\":\"Acta Neuropsychiatrica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2024-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Neuropsychiatrica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1017/neu.2024.7\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/2/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Neuropsychiatrica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1017/neu.2024.7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/19 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
摘要
研究目的阿尔茨海默病（AD）与自传体过度泛化（即患者倾向于检索一般而非具体的个人记忆）有关。AD 还与幻觉有关。我们研究了 AD 患者自传体过度泛化与幻觉之间的关系：方法：我们邀请 28 名轻度 AD 患者检索自传体记忆，同时评估这些患者的幻觉发生情况：结果：分析表明，幻觉与患者自传体过度泛化之间存在明显的相关性：结论：因幻觉而苦恼的AD患者可能会表现出自传体过度泛化，以避免检索可能与幻觉有关的苦恼信息。然而，在我们的研究中观察到的幻觉也可归因于其他因素，如AD患者的整体认知能力下降。
On hallucinations and memory: the relationship between hallucinations and autobiographical overgenerality in Alzheimer's Disease.
Objectives: Alzheimer's disease (AD) has been associated with autobiographical overgenerality (i.e. a tendency of patients to retrieve general rather than specific personal memories). AD has also been associated with hallucinations. We investigated the relationship between autobiographical overgenerality and hallucinations in AD.
Methods: We invited 28 patients with mild AD to retrieve autobiographical memories, and we also evaluated the occurrence of hallucinations in these patients.
Results: Analysis demonstrated significant correlations between hallucinations and autobiographical overgenerality in the patients.
Conclusion: AD patients who are distressed by hallucinations may demonstrate autobiographical overgenerality as a strategy to avoid retrieving distressing information that may be related with hallucinations. However, hallucinations as observed in our study can be attributed to other factors such as the general cognitive decline in AD.
期刊介绍：
Acta Neuropsychiatrica is an international journal focussing on translational neuropsychiatry. It publishes high-quality original research papers and reviews. The Journal''s scope specifically highlights the pathway from discovery to clinical applications, healthcare and global health that can be viewed broadly as the spectrum of work that marks the pathway from discovery to global health.
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