Xia Yang, Caihong Lin, Qingyun Wu, Lvye Li, Xiaofeng Mei
{"title":"低钠饮食与充足的水摄入可提高梅尼埃病的临床疗效。","authors":"Xia Yang, Caihong Lin, Qingyun Wu, Lvye Li, Xiaofeng Mei","doi":"10.1080/00016489.2024.2315302","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Ménière's disease (MD) is a common idiopathic inner ear disorder in otorhinolaryngology characterized by recurrent episodes of vertigo, fluctuating sensorineural hearing loss, tinnitus and ear fullness.</p><p><strong>Objective: </strong>To study the effects of low-sodium diet with adequate water intake on the clinical efficacy in MD.</p><p><strong>Methods: </strong>Fifty patients diagnosed with stage-3 unilateral MD were randomly divided into control group(<i>n</i> = 25) and experimental group(<i>n</i> = 25). The control group was given routine medication therapy, and the experimental group was restricted to an sodium intake of 1500 mg/d and a water intake of 35 ml/kg/d based in addition to the routine medication therapy. The two groups were assessed using pure tone audiometry, electrocochleography, Tinnitus Handicap Inventory (THI), and Dizziness Handicap Inventory (DHI).</p><p><strong>Results: </strong>The pure tone audiometry and electrocochleography showed better improvements after treatment in the experimental group than the control group (<i>p</i> < 0.05). The THI improved values in the experimental group were significantly higher than the control group (<i>p</i> < 0.001). The DHI improved values in the experimental group were significantly higher than the control group (<i>p</i> = 0.004).</p><p><strong>Conclusions and significance: </strong>Low-sodium diet with adequate water intake improved the hearing and alleviated vertigo and tinnitus in MD patients.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Low-sodium diet with adequate water intake improved the clinical efficacy in Ménière's disease.\",\"authors\":\"Xia Yang, Caihong Lin, Qingyun Wu, Lvye Li, Xiaofeng Mei\",\"doi\":\"10.1080/00016489.2024.2315302\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Ménière's disease (MD) is a common idiopathic inner ear disorder in otorhinolaryngology characterized by recurrent episodes of vertigo, fluctuating sensorineural hearing loss, tinnitus and ear fullness.</p><p><strong>Objective: </strong>To study the effects of low-sodium diet with adequate water intake on the clinical efficacy in MD.</p><p><strong>Methods: </strong>Fifty patients diagnosed with stage-3 unilateral MD were randomly divided into control group(<i>n</i> = 25) and experimental group(<i>n</i> = 25). The control group was given routine medication therapy, and the experimental group was restricted to an sodium intake of 1500 mg/d and a water intake of 35 ml/kg/d based in addition to the routine medication therapy. The two groups were assessed using pure tone audiometry, electrocochleography, Tinnitus Handicap Inventory (THI), and Dizziness Handicap Inventory (DHI).</p><p><strong>Results: </strong>The pure tone audiometry and electrocochleography showed better improvements after treatment in the experimental group than the control group (<i>p</i> < 0.05). The THI improved values in the experimental group were significantly higher than the control group (<i>p</i> < 0.001). The DHI improved values in the experimental group were significantly higher than the control group (<i>p</i> = 0.004).</p><p><strong>Conclusions and significance: </strong>Low-sodium diet with adequate water intake improved the hearing and alleviated vertigo and tinnitus in MD patients.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1080/00016489.2024.2315302\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/2/20 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/00016489.2024.2315302","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/2/20 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Low-sodium diet with adequate water intake improved the clinical efficacy in Ménière's disease.
Background: Ménière's disease (MD) is a common idiopathic inner ear disorder in otorhinolaryngology characterized by recurrent episodes of vertigo, fluctuating sensorineural hearing loss, tinnitus and ear fullness.
Objective: To study the effects of low-sodium diet with adequate water intake on the clinical efficacy in MD.
Methods: Fifty patients diagnosed with stage-3 unilateral MD were randomly divided into control group(n = 25) and experimental group(n = 25). The control group was given routine medication therapy, and the experimental group was restricted to an sodium intake of 1500 mg/d and a water intake of 35 ml/kg/d based in addition to the routine medication therapy. The two groups were assessed using pure tone audiometry, electrocochleography, Tinnitus Handicap Inventory (THI), and Dizziness Handicap Inventory (DHI).
Results: The pure tone audiometry and electrocochleography showed better improvements after treatment in the experimental group than the control group (p < 0.05). The THI improved values in the experimental group were significantly higher than the control group (p < 0.001). The DHI improved values in the experimental group were significantly higher than the control group (p = 0.004).
Conclusions and significance: Low-sodium diet with adequate water intake improved the hearing and alleviated vertigo and tinnitus in MD patients.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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