Agnes Giovanni Marsius, Satria Hidayat, Damar Rastri Adhika, Akhmad Zein Eko Mustofa, Veinardi Suendo, Heni Rachmawati
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引用次数: 0
摘要
有人建议将 CeO2 纳米粒子(纳米铈)作为一种具有抗氧化特性和类似紫外线吸收性能的替代物理防晒剂。用掺杂银和掺杂镍的纳米铈绿色合成的掺杂纳米铈具有较低的催化活性和生物安全特性。使用 X 射线衍射 (XRD)、透射电子显微镜 (TEM)、Rancimat 仪器和紫外可见分光光度计对掺杂的纳米铈进行了表征,以测定其防晒系数 (SPF)。X 射线衍射和透射电子显微镜分析表明,纳米铈已成功形成纳米级尺寸,由于添加掺杂剂导致晶体缺陷现象,晶体尺寸发生了变化。通过 Rancimat 试验和带隙能分析来评估氧化稳定性和活性氧的形成,结果证实添加掺杂剂会降低材料的催化活性,导致掺镍 Ce 的孵育时间(11.81 h)比掺银 Ce(10.58 h)和不掺银 Ce(10.30 h)长。使用基于初榨椰子油(VCO)乳液的防晒原型薄层技术测量了体外 SPF 值,10% 掺银 Ce 和 10% 掺镍 Ce 的 SPF 值分别为 10.862 和 5.728。添加掺杂剂的纳米铈可降低催化活性,并在体外紫外线屏蔽性能测试中表现良好;因此,掺银和掺镍的纳米铈有望成为替代物理防晒剂的候选材料。
Effect of Ag and Ni-Doped Cerium Oxide Nanoparticles on the Formation of ROS and Evaluation as an Alternative Physical Sunscreen Material
CeO2 nanoparticles (nanoceria) were proposed as an alternative physical sunscreen agent with antioxidant properties and comparable UV absorption performance. Green synthesis of nanoceria with Ag and Ni dopants resulted in doped nanoceria with lower catalytic activity and biologically-safe characteristics. The doped nanoceria was characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), Rancimat Instrument, and UV-Vis Spectrophotometer for SPF (Sun Protection Factor) determination. XRD and TEM analysis showed that nanoceria had been successfully formed in nanoscale-sized with a change in crystallite size due to the crystal defect phenomenon caused by dopant addition. While the Rancimat test and band gap energy analysis were conducted to evaluate the oxidative stability and reactive oxygen species formation, it was confirmed that dopant addition could decrease catalytic activity of material, resulting in Ni-doped Ce with a longer incubation time (11.81 h) than Ag-doped Ce (10.58 h) and non-doped Ce (10.30 h). In-vitro SPF value was measured using the thin layer technique of sunscreen prototype with Virgin Coconut Oil (VCO)-based emulsion, which yielded 10.862 and 5.728 SPF values for 10% Ag-doped Ce and 10% Ni-doped Ce, respectively. The dopant addition of nanoceria could reduce catalytic activity and give a decent in vitro UV-shielding performance test; thus, Ag and Ni-doped nanoceria could be seen as promising candidates for alternative physical sunscreen agents.
期刊介绍:
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