透视当前和过去的吸入疗法模式。

IF 5.7 2区 生物学 Microbial Biotechnology Pub Date : 2024-02-22 DOI:10.1111/1751-7915.14419
José Canto Mangana, Kelsey Aguirre Schilder, José Ignacio Bretones-Pedrinaci, Ana Rosa Márquez Blesa, Fermín Sánchez de Medina, Olga Martínez-Augustin, Abdelali Daddaoua
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引用次数: 0

摘要

吸入是抗哮喘和慢性阻塞性肺病(COPD)药物的首选给药途径。使用这种途径已证明对这些疾病和其他疾病具有疗效,而且起效迅速,全身暴露极少,从而降低了不良反应的风险。因此,本简介涵盖了一系列有趣的吸入器作用模式,揭示了它们的分子机制以及在抗哮喘、慢性阻塞性肺病和抗菌吸入疗法中的临床应用。因此,它不仅丰富了我们对吸入疗法分子复杂性的理解,还全面概述了临床和抗菌吸入疗法不断发展的情况。在此过程中,它强调了微生物学和生物技术在推进利用吸入力量的治疗方法方面的关键作用。
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A perspective current and past modes of inhalation therapy

Inhalation is the preferred route of delivery for anti-asthma and chronic obstructive pulmonary disease (COPD) drugs. The use of this route has demonstrated efficacy in these and other conditions, it offers rapid onset of action, and is associated with minimal systemic exposure, thereby reducing the risk of adverse effects. Therefore, the current brief covers an interesting collection of inhaler action modes, shedding light on their molecular mechanisms and clinical applications for anti-asthma, COPD and antibacterial inhalation therapy. Hence, not only enriches our understanding of inhalation therapy molecular intricacies but also provides a comprehensive overview of the evolving landscape in clinical and antibacterial inhalation therapy. In doing so, it underscores the pivotal role of microbiology and biotechnology in advancing therapeutic approaches that harness the power of inhalation.

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来源期刊
Microbial Biotechnology
Microbial Biotechnology Immunology and Microbiology-Applied Microbiology and Biotechnology
CiteScore
11.20
自引率
3.50%
发文量
162
审稿时长
1 months
期刊介绍: Microbial Biotechnology publishes papers of original research reporting significant advances in any aspect of microbial applications, including, but not limited to biotechnologies related to: Green chemistry; Primary metabolites; Food, beverages and supplements; Secondary metabolites and natural products; Pharmaceuticals; Diagnostics; Agriculture; Bioenergy; Biomining, including oil recovery and processing; Bioremediation; Biopolymers, biomaterials; Bionanotechnology; Biosurfactants and bioemulsifiers; Compatible solutes and bioprotectants; Biosensors, monitoring systems, quantitative microbial risk assessment; Technology development; Protein engineering; Functional genomics; Metabolic engineering; Metabolic design; Systems analysis, modelling; Process engineering; Biologically-based analytical methods; Microbially-based strategies in public health; Microbially-based strategies to influence global processes
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