破解非营养型甜味剂之谜

IF 0.7 4区 医学 Q4 ENDOCRINOLOGY & METABOLISM International Journal of Diabetes in Developing Countries Pub Date : 2024-02-24 DOI:10.1007/s13410-024-01323-7
Sachdev Meenakshi, Viswanathan Mohan
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引用次数: 0

摘要

背景本评论探讨了非营养型甜味剂的现状,进一步深入研究了非营养型甜味剂(NNS)消费的历史轨迹和当代激增,以及伴随而来的有关其安全性的争议。此外,它还研究了 NNS 对肠道微生物群的影响,并探讨了与妊娠糖尿病、胎儿暴露和后代健康有关的问题。结果虽然由于潜在风险,建议在怀孕和胎儿发育期间谨慎使用 NNS,但如果谨慎使用较低量的 NNS,则有望达到体重管理和短期饮食目标。该评论强调,有必要开展全面、长期的研究,以指导以证据为导向的政策和指南。结论虽然文章强调了围绕非营养性甜味剂(NNS)的复杂性和争论,但也揭示了其积极的方面。在印度,甜味剂的摄入量相对较低,且主要限于饮料(茶或咖啡),因此非营养型甜味剂似乎是安全的,但提倡谨慎使用。文章强调了关于使用 NNS 的公众教育的价值,并得出结论:总体而言,适量摄入 NNS 是相当安全的。文章最后提出了在印度使用 NNS 的明确指导原则,强调了做出明智决策和持续研究以阐明 NNS 对健康的广泛影响的必要性。
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Decoding the mystery of non-nutritive sweeteners

Background

This commentary explores the landscape of non-nutritive sweeteners, further delves into the historical trajectory and the contemporary surge in the consumption of non-nutritive sweeteners (NNS), along with the accompanying controversies concerning their safety.

Objective

The aim is to provide a comprehensive understanding of the influences of NNS, drawn from global studies and diverse perspectives.

Methods

The commentary synthesizes findings from global studies, notably the NutriNet-Santé cohort, exploring associations between specific NNS and health consequences such as cerebrovascular events and malignancies. Additionally, it examines the research on consequences of NNS on gut microbiota and explores concerns linked to gestational diabetes, fetal exposure, and health of the offspring.

Results

While caution is advised during pregnancy and fetal development due to potential risks, NNS show promise in weight management and short-term dietary goals when used cautiously in lower amounts. The commentary underscores the necessity for inclusive, long-term studies to guide evidence-driven policies and guidelines.

Conclusion

While the article underscores the complexities and debates surrounding non-nutritive sweeteners (NNS), it also sheds light on the positive aspects. In the Indian context, where the intake of sweeteners is relatively low and mainly limited to beverages (tea or coffee), NNS appear to be safe, but prudent use is advocated. The article emphasizes the value of public education on NNS usage and concludes that, overall, NNS are reasonably safe when consumed in moderation. Continued research is needed to elucidate their intricate effects on health and impact on global health outcomes.

Implications

The article concludes with clear guidelines for using NNS in India, highlighting the need for informed decision-making and ongoing research to elucidate their broader health consequences.

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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
109
审稿时长
6 months
期刊介绍: International Journal of Diabetes in Developing Countries is the official journal of Research Society for the Study of Diabetes in India. This is a peer reviewed journal and targets a readership consisting of clinicians, research workers, paramedical personnel, nutritionists and health care personnel working in the field of diabetes. Original research articles focusing on clinical and patient care issues including newer therapies and technologies as well as basic science issues in this field are considered for publication in the journal. Systematic reviews of interest to the above group of readers are also accepted.
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