评估使用智能手机进行自我测量的新型便携式角膜地形图系统:一项试点研究

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摘要

摘要 目的 我们在此提出使用 "KeraVio Ring",它是一种基于自拍的便携式智能手机角膜地形图系统,以 Placido 环形视频角膜塑形镜为基础。本研究的目的是评估和比较 KeraVio Ring 与传统角膜断层扫描图像之间的角膜参数。 方法 我们设计的 KeraVio Ring 是一种由 3D 打印的 LED 环组成的设备,用于生成可连接到智能手机的 Placido 环。两个 LED 环连接到一个锥形装置上,两个角膜都被照亮。使用连接到智能手机上的 KeraVio Ring 拍摄自拍照,无需任何检查人员的协助。拍摄到的角膜上的 Placido 环通过智能软件进行分析,计算角膜参数。患者包括正常眼、角膜炎眼或接受过 LASIK 治疗的眼。每个受试者还进行了眼前节光学相干断层扫描(AS-OCT)。 结果 我们发现,KeraVio 光环和 AS-OCT 获得的最陡和最平角膜度数、角膜散光和矢量成分之间存在高度相关性。在正常眼、角膜炎眼和 LASIK 治疗眼的受试者中,两种设备的角膜散光平均差异分别为 -0.8 ± 1.4 屈光度 (D)(95% 一致限值 (LoA),-3.6 至 2.0)、-1.8 ± 3.7 D(95% 一致限值,-9.1 至 5.5)和-1.5 ± 1.3 D(95% 一致限值,-4.0 至 1.1)。 结论 实验结果表明,KeraVio 角膜环获得的角膜参数与 AS-OCT 获得的参数具有相关性。KeraVio Ring 提供了一种基于自拍的便携式角膜地形图工具,有望满足尚未满足的需求。
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Evaluation of a new portable corneal topography system for self-measurement using smartphones: a pilot study

Abstract

Purpose

Herein, we propose the use of the “KeraVio Ring”, which is a portable, selfie-based, smartphone-attached corneal topography system that is based on the Placido ring videokeratoscope. The goal of this study was to evaluate and compare corneal parameters between KeraVio Ring and conventional corneal tomography images.

Methods

We designed the KeraVio Ring as a device comprising 3D-printed LED rings for generating Placido rings that can be attached to a smartphone. Two LED rings are attached to a cone-shaped device, and both corneas are illuminated. Selfies were taken using the KeraVio Ring attached to the smartphone without assistance from any of the examiners. Captured Placido rings on the cornea were analysed by intelligent software to calculate corneal parameters. Patients with normal, keratoconus, or LASIK-treated eyes were included. Anterior segment optical coherence tomography (AS-OCT) was also performed for each subject.

Results

We found highly significant correlations between the steepest and flattest keratometry, corneal astigmatism, and vector components obtained with the KeraVio Ring and AS-OCT. In subjects with normal, keratoconus, and LASIK-treated eyes, the mean difference in corneal astigmatism between the two devices was -0.8 ± 1.4 diopters (D) (95% limits of agreement (LoA), -3.6 to 2.0), -1.8 ± 3.7 D (95% LoA, -9.1 to 5.5), and -1.5 ± 1.3 D (95% LoA, -4.0 to 1.1), respectively.

Conclusions

The experimental results showed that the corneal parameters obtained by the KeraVio Ring were correlated with those obtained with AS-OCT. The KeraVio Ring has the potential to address an unmet need by providing a tool for portable selfie-based corneal topography.

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