振荡测量法在哮喘中的作用。

IF 2.8 3区 医学 Q2 RESPIRATORY SYSTEM Current Opinion in Pulmonary Medicine Pub Date : 2024-05-01 Epub Date: 2024-02-15 DOI:10.1097/MCP.0000000000001057
Patrick A Donohue, David A Kaminsky
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引用次数: 0

摘要

审查目的:振荡测定法是一种无创肺功能测试,在肺部疾病评估中已获得了极大的关注。目前,示波法主要是一种研究工具,但越来越多的证据支持其临床应用。本综述介绍了最近对示波法在哮喘诊断和治疗中的作用进行评估的工作:大量观察性数据支持示波法区分健康人和有呼吸道症状或肺部疾病的人的能力。振荡测定法作为一项单独的哮喘诊断测试可能并不实用,但与其他肺功能测试结合使用可提高其诊断能力。振荡测定法可以检测哮喘患者的外周气道功能障碍,这与症状和病情加重的风险有关。为了帮助指导未来的研究,已针对特定振荡测量变量制定了最小临床重要差异。振荡测量法可用于监测对生物疗法的反应,并有可能为个别患者提供个性化治疗。振荡测量法还有可能揭示肥胖症哮喘病理生理学的独特方面。需要更多的研究来支持其常规临床应用。
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The role of oscillometry in asthma.

Purpose of review: Oscillometry is a noninvasive pulmonary function test that has gained significant interest in the evaluation of lung disease. Currently, oscillometry is primarily a research tool, but there is a growing body of evidence supporting its clinical use. This review describes the recent work evaluating the role of oscillometry in the diagnosis and treatment of asthma.

Recent findings: A large body of observational data supports the ability of oscillometry to distinguish healthy individuals from those with respiratory symptoms or lung disease. Oscillometry may not be as useful as an isolated diagnostic test in asthma, but the combination with other pulmonary function tests may improve its diagnostic ability. Oscillometry can detect peripheral airways dysfunction in asthma, which is associated with symptoms and the risk for exacerbations. To help guide future research, minimal clinically important differences for specific oscillometry variables have been developed. Oscillometry may be useful in monitoring the response to biological therapy and has potential for personalizing treatment for individual patients. Oscillometry also has potential in uncovering unique aspects of the pathophysiology of asthma in obesity.

Summary: Oscillometry is a promising tool in the diagnosis and management of asthma. More research is needed to support its routine clinical use.

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来源期刊
CiteScore
6.20
自引率
0.00%
发文量
109
审稿时长
6-12 weeks
期刊介绍: ​​​​​​Current Opinion in Pulmonary Medicine is a highly regarded journal offering insightful editorials and on-the-mark invited reviews, covering key subjects such as asthma; cystic fibrosis; infectious diseases; diseases of the pleura; and sleep and respiratory neurobiology. Published bimonthly, each issue of Current Opinion in Pulmonary Medicine introduces world renowned guest editors and internationally recognized academics within the pulmonary field, delivering a widespread selection of expert assessments on the latest developments from the most recent literature.
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