麻风病人及其家庭接触者皮肤中猫嗜血杆菌素水平的比较。

Q3 Medicine Acta medica academica Pub Date : 2023-12-01 DOI:10.5644/ama2006-124.424

Fifa Argentina, Oki Suwarsa, Hendra Gunawan, Afiat Berbudi

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摘要

研究目的本研究旨在比较麻风病人和麻风病接触者皮肤中的chelicidin水平：本研究是一项横断面分析观察性研究。54名研究对象参与了这项研究。他们包括麻风病人、家庭接触者和健康人。采用酶联免疫吸附法测定了白细胞介素的水平。数据分析采用 SPSS 软件，并进行了单变量和双变量分析：结果：麻风杆菌组的猫酪素水平（256.8±22.9 pg/ml）高于接触组（25.9±2.7 pg/ml）。同样，接触组的柔毛素水平也高于健康对照组（1.4±0.1 pg/ml）。从统计学角度看，不同组间的猫辣素水平存在差异：麻风病人体内的柔毛素水平高于家庭接触者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A Comparison of Cathelicidin Levels in the Skin of Leprosy Patients and Their Household Contacts.

Objective: This study aimed to compare cathelicidin levels in the skin of leprae patients and leprae contacts.

Patients and methods: This research is an analytic observational study with a cross-sectional approach. Fifty-four research subjects participated in this study. They consisted of leprae patients, household contacts, and healthy individuals. Cathelicidin levels were measured using the ELISA method. Data analysis was carried out with the help of SPSS software, and univariate and bivariate analysis was conducted.

Results: Cathelicidin levels in the leprae group (256.8±22.9 pg/ml) were higher than in the contact group (25.9±2.7 pg/ml). Likewise, the contact group had higher cathelicidin levels than healthy controls (1.4±0.1 pg/ml). Statistically, there were differences in cathelicidin levels between groups, P<0.050.

Conclusion: Cathelicidin levels in leprae patients were higher than those in household contacts.

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