为澳大利亚现行的国家 COVID-19 指南设计、改进和反思 3 年的日常证据监测工作

Steve McDonald, Tari Turner
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摘要

澳大利亚 COVID-19 国家生活指南于 2020 年 4 月推出,其中包括 200 多条建议,用于指导 COVID-19 患者的临床治疗。在该指南于 2023 年 8 月退役之前,通过日常监测对新证据进行持续监控。本文介绍了证据监测的最初设计(当时整理新型冠状病毒信息的工作尚处于起步阶段,而且经常出现重复)以及在整个大流行期间如何对其进行改进。在广泛的监测来源中,从主要医学期刊、medRxiv 预印本和 PubMed 自动提示中收集的 COVID-19 研究成果在识别时间关键和有影响的证据方面证明是最持久的。本文还探讨了如何利用信息应用程序和通信平台将证据跟踪和监控整合到整个证据工作流程中。最后,我们探讨了活指南的意义,并反思了促成日常监控可行性的因素:明确界定的指南范围;将工作重点放在最大影响上;通过与他人合作尽量减少重复;建立简单而有效的证据管理流程;以及人员从一开始就持续参与的价值。澳大利亚的 COVID-19 活指南以一种新颖的证据监测方法为基础,这种方法是可行的,而且对于将 COVID-19 活指南维持 3 年以上至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Designing, refining and reflecting on 3 years of daily evidence surveillance for Australia's living national COVID-19 guidelines

Australia's national living guidelines for COVID-19 were launched in April 2020 and include over 200 recommendations to guide the clinical care of patients with COVID-19. Until the guidelines were retired in August 2023, new evidence was continually monitored through daily surveillance. This paper describes the initial design for evidence surveillance (at a time when efforts to collate information on the novel coronavirus were in their infancy and often duplicative) and how it was refined throughout the pandemic. Among the wide range of sources monitored, the collections of COVID-19 research from leading medical journals, medRxiv preprints and PubMed auto alerts proved the most enduring in identifying time-critical and impactful evidence. The paper also explores how evidence was tracked and surveillance integrated into the overall evidence workflow by using messaging apps and communication platforms. Finally, we consider the implications for living guidelines and reflect on factors that contributed to the feasibility of daily surveillance: the clearly defined scope of the guidelines; focusing efforts on maximum impact; minimizing duplication by partnering with others; setting up simple but effective processes for managing evidence; and the value of continuous involvement of personnel from the outset. Australia's living COVID-19 guidelines were underpinned by a novel approach to evidence surveillance that was feasible and essential in maintaining COVID-19 living guidelines for over 3 years.

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