西班牙裔患者中仍存在差异:完成评估、排队等候和接受肾移植。

IF 1.9 Q3 TRANSPLANTATION Transplantation Direct Pub Date : 2024-02-26 eCollection Date: 2024-03-01 DOI:10.1097/TXD.0000000000001595
Elisa J Gordon, Jungwha Lee, Raymond Kang, Jefferson Uriarte, Juan Carlos Caicedo
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引用次数: 0

摘要

背景:与非西班牙裔白人(NHW)患者相比,西班牙裔患者接受肾移植(KT)的人数少得不成比例。在这项观察性研究中,我们评估了西班牙裔患者在完成肾移植评估步骤方面的差异:利用 2011 年 1 月至 2020 年 3 月期间在 4 个移植中心接受评估的西班牙裔和非西班牙裔白人患者的医疗记录,我们采用连续 Cox 模型比较了西班牙裔和非西班牙裔白人患者在接受 KT 之前完成评估流程各步骤的情况:在所有 5197 名接受评估的患者中(西班牙裔患者 n = 2473;非西班牙裔患者 n = 2724),西班牙裔患者获得胰肾(KP)委员会批准的风险比非西班牙裔患者低 8%(调整后危险比 [aHR],0.92;95% 置信区间 (CI),0.86-0.98;P = 0.015)。在 3492 名获得 KP 委员会批准的患者中,西班牙裔患者被列入候选名单的风险比非华裔患者低 13%(aHR,0.87;95% CI,0.81-0.94;P = 0.004)。在 3382 名被列入候选名单的患者中,西班牙裔患者接受 KT 的风险比非华裔患者低 11%(aHR,0.89;95% CI,0.81-0.97;P = 0.011)。在所有接受评估的患者中,西班牙裔患者接受 KT 的风险比白种人低 16%(aHR,0.84;95% CI,0.76-0.92;P = 0.0002):我们的研究发现,西班牙裔患者获得KP委员会批准、列入候选名单以及接受KT(尤其是活体肾移植)的人数都少于非华裔患者。对评估过程进行更严格的监督可能有助于患者克服获得 KT 的困难。
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Disparities Persist Among Hispanic Patients: Completing Evaluation, Waitlisting, and Receiving a Kidney Transplant.

Background: Hispanic patients receive disproportionately fewer kidney transplants (KT) than non-Hispanic White (NHW) patients. In this observational study, we evaluated disparities in completing evaluation steps to KT among Hispanic patients.

Methods: Using medical records of Hispanic and NHW patients initiating evaluation at 4 transplant centers from January 2011 to March 2020, we performed sequential Cox models to compare Hispanic versus NHW patients reaching each step of the evaluation process until receiving a KT.

Results: Among all 5197 patients (Hispanic n = 2473; NHW n = 2724) initiating evaluation, Hispanic patients had 8% lower risk to be approved by the kidney pancreas (KP) committee than NHW patients (adjusted hazard ratio [aHR], 0.92; 95% confidence intervals (CI), 0.86-0.98; P = 0.015). Among 3492 patients approved by the KP committee, Hispanic patients had 13% lower risk to be waitlisted than NHW patients (aHR, 0.87; 95% CI, 0.81-0.94; P = 0.004). Among 3382 patients who were waitlisted, Hispanic patients had 11% lower risk than NHW patients to receive KT (aHR, 0.89; 95% CI, 0.81-0.97; P = 0.011). Among all patients initiating evaluation, Hispanic patients had a 16% lower risk than NHW patients to reach KT (aHR, 0.84; 95% CI, 0.76-0.92; P = 0.0002).

Conclusions: Our study found that disproportionately fewer Hispanic patients were approved by the KP committee, were waitlisted, and received a KT, particularly a living donor kidney transplant, than NHW patients. Closer oversight of the evaluation process may help patients overcome challenges in access to KT.

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来源期刊
Transplantation Direct
Transplantation Direct TRANSPLANTATION-
CiteScore
3.40
自引率
4.30%
发文量
193
审稿时长
8 weeks
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