Ayumi Niwa, Masahiro Hayashi, Jun Yonetamari, Motohiro Nakamura, Yuta Yokobori, Sodai Yokoyama, Mizuki Ogawa, Rina Ichioka, Ryosuke Kikuchi, Hiroyuki Okura, Shinji Ogura, Nobuyuki Tetsuka, Kaori Tanaka, Hisashi Baba
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引用次数: 0
摘要
我们在此报告了首例由鲁氏猪杆菌(Pigmentibacter ruber)引起的坏死性筋膜炎病例。通过生化鉴定和基质辅助激光解吸/电离飞行时间质谱(MALDI-TOF MS)无法确定分离出的菌株。通过 16S 核糖体 RNA 和全基因组测序,确定分离出的菌株为 P. ruber。虽然这种细菌对人类的致病性仍有很多未知之处,但它已被揭示可导致危及生命的感染,如败血症和坏死性筋膜炎。由于该分离株对β-内酰胺类药物有很强的抗药性,因此很难通过抗菌疗法进行治疗。因此,需要进一步记录病例并进行分析。
First Case of Necrotizing Fasciitis and Septicemia Caused by Pigmentibacter ruber.
We report the first case of necrotizing fasciitis caused by Pigmentibacter ruber. The isolated strain could not be identified by biochemical characterization or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry but was identified as P. ruber by 16S ribosomal RNA and whole-genome sequencing. Although much remains unknown about the pathogenicity of this bacterial species in humans, it has been shown to cause life-threatening infections such as septicemia and necrotizing fasciitis. Because the isolate was highly resistant to β-lactams, it was difficult to treat with antimicrobial therapy. Thus, further documentation of cases and analyses are required.
期刊介绍:
Japanese Journal of Infectious Diseases (JJID), an official bimonthly publication of National Institute of Infectious Diseases, Japan, publishes papers dealing with basic research on infectious diseases relevant to humans in the fields of bacteriology, virology, mycology, parasitology, medical entomology, vaccinology, and toxinology. Pathology, immunology, biochemistry, and blood safety related to microbial pathogens are among the fields covered. Sections include: original papers, short communications, epidemiological reports, methods, laboratory and epidemiology communications, letters to the editor, and reviews.