Jens H Kuhn, Artem Babaian, Laura M Bergner, Paul Dény, Dieter Glebe, Masayuki Horie, Eugene V Koonin, Mart Krupovic, Sofia Paraskevopoulou, Marcos de la Peña, Teemu Smura, Jussi Hepojoki
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引用次数: 0
摘要
科尔米亚病毒科（Kolmioviridae）是负意义 RNA 病毒的一个家族，其基因组为 1.5-1.7 kb 的环状病毒，主要存在于哺乳动物、两栖动物、鸟类、鱼类、昆虫和爬行动物体内。例如，Deltaviruses 可导致人类重症肝炎。Kolmiovirids 编码三角抗原（DAg），并利用宿主细胞 DNA 引导的 RNA 聚合酶 II 和其基因组和抗原组中编码的核酶进行复制。它们需要与进化无关的辅助病毒提供包膜，并结合辅助病毒蛋白形成感染性颗粒。本文是国际病毒分类委员会（ICTV）关于 Kolmioviridae 科的报告摘要，可在 ictv.global/report/kolmioviridae 网站上查阅。
Kolmioviridae is a family for negative-sense RNA viruses with circular, viroid-like genomes of about 1.5-1.7 kb that are maintained in mammals, amphibians, birds, fish, insects and reptiles. Deltaviruses, for instance, can cause severe hepatitis in humans. Kolmiovirids encode delta antigen (DAg) and replicate using host-cell DNA-directed RNA polymerase II and ribozymes encoded in their genome and antigenome. They require evolutionary unrelated helper viruses to provide envelopes and incorporate helper virus proteins for infectious particle formation. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Kolmioviridae, which is available at ictv.global/report/kolmioviridae.
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JOURNAL OF GENERAL VIROLOGY (JGV), a journal of the Society for General Microbiology (SGM), publishes high-calibre research papers with high production standards, giving the journal a worldwide reputation for excellence and attracting an eminent audience.
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