成人下肢软组织肉瘤皮瓣重建整形方法的系统性回顾。

Myles N LaValley, David Dugue, Sarah E Diaddigo, Kevin G Kuonqui, Wakenda K Tyler, Jarrod T Bogue
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引用次数: 0

摘要

背景:矫形方法改变了治疗各种下肢病变患者的方式。通过系统回顾,我们旨在分析下肢软组织肉瘤成人患者接受整形皮瓣管理方法治疗后的疗效:根据《系统综述和荟萃分析首选报告项目》(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)指南,我们在Pubmed、Embase和Web of Science数据库中搜索了从开始到2023年4月的成人下肢软组织肉瘤切除术与整形外科皮瓣重建术:结果:在去除重复文章、筛选标题和摘要以及全文审阅后,26 篇文章被接受纳入。总平均随访时间为(32.0 ± 24.3)个月。65.5%(487/743)的重建使用了微血管游离皮瓣,34.5%(256/743)使用了局部皮瓣。85.8%(307/358)的患者术后可以行走。21%的患者在随访期间需要进行翻修手术。肢体挽救率为93.4%(958/1,026)。在汇总的手术结果中,22.2%(225/1,012)的患者经历了围手术期并发症:讨论:我们的研究表明,虽然下肢软组织肉瘤重建术的并发症发生率有待进一步优化,但多学科皮瓣重建方法的肢体挽救率和术后功能活动率都很高。
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A Systematic Review of the Orthoplastic Approach in Adult Lower Extremity Soft Tissue Sarcoma Flap Reconstruction.

Background: The orthoplastic approach to patient care has changed the way patients with a wide variety of lower extremity pathology are treated. Through a systematic review, we aim to analyze outcomes in adult patients with lower extremity soft tissue sarcomas who undergo an orthoplastic flap management approach to their care.

Methods: A systematic review of adult lower extremity soft tissue sarcoma excision with plastic surgery flap reconstruction was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines searching the Pubmed, Embase, and Web of Science databases from inception to April 2023.

Results: After removal of duplicates, title and abstract screening, and full-text review, 26 articles were accepted for inclusion. The total mean follow-up duration was 32.0 ± 24.3 months. Reconstruction used microvascular free flaps in 65.5% (487/743), while 34.5% (256/743) were local flaps. 85.8% (307/358) of patients ambulated postoperatively. Revision surgery was required in 21% of patients during their respective follow-up periods. The limb salvage rate was 93.4% (958/1,026). Among pooled surgical outcomes, 22.2% (225/1,012) of patients experienced a perioperative complication.

Discussion: Our study demonstrates that although complication rates in lower extremity soft tissue sarcoma reconstruction may be further optimized, a multidisciplinary flap reconstructive approach provides high rates of limb salvage and functional postoperative ambulation.

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CiteScore
2.60
自引率
6.70%
发文量
282
审稿时长
8 weeks
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