Min Hao, Wenhan Wang, Anil Kumar, Wan Hairul Anuar Kamaruddin, Syafiqah Saidin, Nik Ahmad Nizam Nik Malek, Jerome Claverie, Hong Liu
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Magnetic hydroxyapatite nanobelt-stem cell hybrid spheroids for remotely patterning bone tissues (1/2024)
In this article number 10.1002/bmm2.12059, Min Hao, Wenhan Wang and their co-workers developed a magnetic ferroferric oxide-hydroxyapatite-polydopamine (Fe3O4-HAp-PDA) nanobelts to assemble mesenchymal stem cells (MSCs) into a three-dimensional stem cell spheroid for patterning bone tissue. The incorporation of superparamagnetic Fe3O4 nanospheres and the calcium-rich composition of the nanobelts successfully accelerates the osteogenic differentiation of MSCs and allows for remote manipulation of the spheroid fusion into bone tissue, providing a viable method for on-demand bone regeneration.
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