磁性羟基磷灰石纳米带-干细胞杂交球体用于远程模式化骨组织 (1/2024)

BMEMat Pub Date : 2024-03-01 DOI:10.1002/bmm2.12074
Min Hao, Wenhan Wang, Anil Kumar, Wan Hairul Anuar Kamaruddin, Syafiqah Saidin, Nik Ahmad Nizam Nik Malek, Jerome Claverie, Hong Liu
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引用次数: 0

摘要

在这篇编号为10.1002/bmm2.12059的文章中,郝敏、王文汉及其合作者开发了一种磁性氧化铁-羟基磷灰石-多巴胺(Fe3O4-HAp-PDA)纳米颗粒,用于将间充质干细胞(MSCs)组装成三维干细胞球体,从而实现骨组织的图案化。超顺磁性 Fe3O4 纳米球的加入和纳米颗粒中富含的钙成分成功地加速了间充质干细胞的成骨分化,并允许远程操纵球体融合成骨组织,为按需骨质再生提供了一种可行的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Magnetic hydroxyapatite nanobelt-stem cell hybrid spheroids for remotely patterning bone tissues (1/2024)

In this article number 10.1002/bmm2.12059, Min Hao, Wenhan Wang and their co-workers developed a magnetic ferroferric oxide-hydroxyapatite-polydopamine (Fe3O4-HAp-PDA) nanobelts to assemble mesenchymal stem cells (MSCs) into a three-dimensional stem cell spheroid for patterning bone tissue. The incorporation of superparamagnetic Fe3O4 nanospheres and the calcium-rich composition of the nanobelts successfully accelerates the osteogenic differentiation of MSCs and allows for remote manipulation of the spheroid fusion into bone tissue, providing a viable method for on-demand bone regeneration.

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