[广西壮族骨质疏松症易感性相关基因多态性研究进展]。

Q4 Medicine 中国医学科学院学报 Pub Date : 2024-02-01 DOI:10.3881/j.issn.1000-503X.15501

Si-Yu Huang, Guang-Bin Ye, Yu-Jia He, Xiao-Yun Bin, Min Zhou, Xiu-Feng Huang

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引用次数: 0

摘要

本文旨在系统总结广西壮族骨质疏松症（OP）易感基因的多态性，这些基因主要编码维生素D受体、雌激素受体、降钙素受体和脂肪连蛋白。这些基因主要编码维生素D受体、雌激素受体、降钙素受体和脂肪连蛋白，比较了壮族与其他民族的基因型和等位基因分布频率，明确了壮族现有的骨质疏松症相关基因和潜在的基因多态性，为后续少数民族骨质疏松症相关基因的研究提供了具有代表性的方案。

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[Progress in Gene Polymorphisms Associated With Osteoporosis Susceptibility in Zhuang Ethnic Group in Guangxi].

The purpose of this paper is to systematically summarize the gene polymorphisms associated with osteoporosis(OP)susceptibility in Zhuang ethnic group in Guangxi.These genes mainly encode vitamin D receptor,estrogen receptor,calcitonin receptor,and adiponectin.The genotype and allele distribution frequency were compared between Zhuang ethnic group and other ethnic groups,which can clarify the existing genes and the potential gene polymorphism associated with OP in Zhuang ethnic group.The findings provide a representative solution for the subsequent research on the genes associated with OP susceptibility in ethnic minorities.

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来源期刊

中国医学科学院学报 Medicine-Medicine (all)

CiteScore

0.60

自引率

0.00%

发文量

6813

期刊介绍： Acta Academiae Medicinae Sinicae was founded in February 1979. It is a comprehensive medical academic journal published in China and abroad, supervised by the Ministry of Health of the People's Republic of China and sponsored by the Chinese Academy of Medical Sciences and Peking Union Medical College. The journal mainly reports the latest research results, work progress and dynamics in the fields of basic medicine, clinical medicine, pharmacy, preventive medicine, biomedicine, medical teaching and research, aiming to promote the exchange of medical information and improve the academic level of medicine. At present, the journal has been included in 10 famous foreign retrieval systems and their databases [Medline (PubMed online version), Elsevier, EMBASE, CA, WPRIM, ExtraMED, IC, JST, UPD and EBSCO-ASP]; and has been included in important domestic retrieval systems and databases [China Science Citation Database (Documentation and Information Center of the Chinese Academy of Sciences), China Core Journals Overview (Peking University Library), China Science and Technology Paper Statistical Source Database (China Science and Technology Core Journals) (China Institute of Scientific and Technological Information), China Science and Technology Journal Paper and Citation Database (China Institute of Scientific and Technological Information)].