高海拔地区年轻人视网膜中央动脉闭塞:稀薄的空气,高风险。

IF 1.6 4区 医学 Q4 BIOPHYSICS High altitude medicine & biology Pub Date : 2024-06-01 Epub Date: 2024-03-01 DOI:10.1089/ham.2023.0101
Vipin Rana, Pradeep Kumar, Sandeepan Bandopadhyay, Vijay K Sharma, Meenu Dangi, Dattakiran Joshi, Sanjay Kumar Mishra, Satyabrat Srikumar, V A Arun
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引用次数: 0

摘要

Rana, Vipin, Pradeep Kumar, Sandeepan Bandopadhyay, Vijay K. Sharma, Meenu Dangi, Dattakiran Joshi, Sanjay Kumar Mishra, Satyabrat Srikumar, and V.A. Arun.高海拔地区青壮年视网膜中央动脉闭塞:稀薄的空气,高风险。00:000-000,2024.--我们介绍了五例年轻安保人员的病例,他们在高海拔地区(HA)工作了至少 6 个月,突然出现单眼视力下降。所有患者均被诊断为视网膜中央动脉闭塞(CRAO)。眼底荧光素血管造影和黄斑光学相干断层扫描证实了这一诊断。这些病例均无任何并发症。所有患者均出现红细胞增多症,其中两人患有高同型半胱氨酸血症。五名患者中有四名在计算机断层扫描血管造影中发现大脑中动脉或颈内动脉(ICA)血栓形成。患者由眼科医生、血液科医生、血管外科医生和神经科医生组成的团队进行治疗。如果是不完全的颈内动脉闭塞,患者将接受手术治疗。但是,对于完全性 ICA 闭塞的病例,则使用抗血小板药物进行保守治疗。该系列病例突出表明,与医管局相关的红细胞增多症和高同型半胱氨酸血症是驻扎在医管局的年轻人发生 CRAO 的重要风险因素。
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Central Retinal Artery Occlusion in Young Adults at High Altitude: Thin Air, High Stakes.

Rana, Vipin, Pradeep Kumar, Sandeepan Bandopadhyay, Vijay K. Sharma, Meenu Dangi, Dattakiran Joshi, Sanjay Kumar Mishra, Satyabrat Srikumar, and V.A. Arun. Central retinal artery occlusion in young adults at high altitude: thin air, high stakes. High Alt Med Biol. 00:000-000, 2024.-We present five cases of young security personnel who were posted at high altitude (HA) for a duration of at least 6 months and presented with a sudden decrease of vision in one eye. The diagnosis of central retinal artery occlusion (CRAO) was made in all patients. Fundus fluorescein angiography and optical coherence tomography of the macula supported the diagnosis. None of these cases had any preexisting comorbidities. Erythrocytosis was noticed in all patients, and two of them had hyperhomocysteinemia. Four out of five patients showed either middle cerebral artery or internal carotid artery (ICA) thrombosis on computed tomography angiography. The patients were managed by a team of ophthalmologist, hematologist, vascular surgeon, and neurologist. In cases of incomplete ICA occlusion, patients were managed surgically. However, in the case of complete ICA occlusion, management was conservative with antiplatelet drugs. This case series highlights HA-associated erythrocytosis and hyperhomocysteinemia as important risk factors for CRAO in young individuals stationed at HA.

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来源期刊
High altitude medicine & biology
High altitude medicine & biology 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.80
自引率
9.50%
发文量
44
审稿时长
>12 weeks
期刊介绍: High Altitude Medicine & Biology is the only peer-reviewed journal covering the medical and biological issues that impact human life at high altitudes. The Journal delivers critical findings on the impact of high altitude on lung and heart disease, appetite and weight loss, pulmonary and cerebral edema, hypertension, dehydration, infertility, and other diseases. It covers the full spectrum of high altitude life sciences from pathology to human and animal ecology.
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