喜马拉雅游牧民族的慢性家庭空气污染和接触模式。

IF 4.1 3区 医学 Q2 ENVIRONMENTAL SCIENCES Journal of Exposure Science and Environmental Epidemiology Pub Date : 2024-03-05 DOI:10.1038/s41370-024-00656-z
Catlin I Powers, Linyan Li, Majid Ezzati, James P Butler, Corwin M Zigler, John D Spengler
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引用次数: 0

摘要

背景:家庭空气污染(HAP)是非传染性疾病的主要风险因素,每年在发展中国家造成数百万人过早死亡。生活在高海拔地区的人群尤其容易受到 HAP 的影响,并导致相关的健康后果:方法:在中国青海海拔 3500 米的喜马拉雅高原上,对 100 户喜马拉雅游牧家庭进行了家庭一氧化碳监测。使用羧基血红蛋白(COHb)作为生物标志物来评估 100 名男性户主和 100 名女性户主的暴露情况。采用线性混合效应模型探讨 COHb 与活动模式之间的关系:结果:与取暖期相比,烹饪期的家庭一氧化碳浓度高出 7 倍(分别为 94 ± 56 ppm 和 13 ± 11 ppm)。在每户人家为期三天的生物标志物监测期间,99% 的受试者至少有一次 COHb 测量值超过了世界卫生组织规定的 2% 的安全水平。烹饪导致 COHb 上升 32%(p 影响声明):这项关于高海拔地区家庭空气污染(HAP)的研究为了解中国青海游牧家庭的暴露模式提供了重要依据。研究发现,烹饪是影响妇女急性一氧化碳 (CO) 暴露的主要因素,而仅取暖就足以使一氧化碳暴露量超过世界卫生组织的指导标准。研究结果表明,仅烹饪干预措施就有可能减少妇女的一氧化碳暴露量,但可能需要同时解决烹饪和取暖问题,才能将一氧化碳暴露量降至世界卫生组织的指导标准以下。这项研究的结果可为今后选择燃料和炉灶的干预措施提供参考,以减少其他人群的氢氟碳化物暴露。
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Chronic household air pollution and exposure patterns among Himalayan nomads.

Background: Household air pollution (HAP) is a major risk factor of non-communicable diseases, causing millions of premature deaths each year in developing nations. Populations living at high altitudes are particularly vulnerable to HAP and associated health outcomes.

Objectives: This study aims to explore the relationships between activity patterns, HAP, and an HAP biomarker among 100 Himalayan nomadic households during both cooking and heating-only periods.

Methods: Household CO was monitored in 100 rural homes in Qinghai, China, at 3500 m on the Himalayan Plateau among Himalayan nomads. Carboxyhemoglobin (COHb) was used as a biomarker to assess exposure among 100 male and 100 female heads of household. Linear mixed-effects models were used to explore the relationship between COHb and activity patterns.

Results: Cooking periods were associated with 7 times higher household CO concentrations compared with heating periods (94 ± 56 ppm and 13 ± 11 ppm, respectively). Over the three-day biomarker-monitoring period in each house, 99% of subjects had at least one COHb measurement exceeding the WHO safety level of 2%. Cooking was associated with a 32% increase in COHb (p < 0.001).

Impact statement: This study on household air pollution (HAP) in high-altitude regions provides important insights into the exposure patterns of nomadic households in Qinghai, China. The study found that cooking is the primary factor influencing acute carbon monoxide (CO) exposure among women, while heating alone is sufficient to elevate CO exposure above WHO guidelines. The results suggest that cooking-only interventions have the potential to reduce HAP exposure among women, but solutions for both cooking and heating may be required to reduce COHb to below WHO guidelines. This study's findings may inform future interventions for fuel and stove selection to reduce HAP and exposure among other populations.

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来源期刊
CiteScore
8.90
自引率
6.70%
发文量
93
审稿时长
3 months
期刊介绍: Journal of Exposure Science and Environmental Epidemiology (JESEE) aims to be the premier and authoritative source of information on advances in exposure science for professionals in a wide range of environmental and public health disciplines. JESEE publishes original peer-reviewed research presenting significant advances in exposure science and exposure analysis, including development and application of the latest technologies for measuring exposures, and innovative computational approaches for translating novel data streams to characterize and predict exposures. The types of papers published in the research section of JESEE are original research articles, translation studies, and correspondence. Reported results should further understanding of the relationship between environmental exposure and human health, describe evaluated novel exposure science tools, or demonstrate potential of exposure science to enable decisions and actions that promote and protect human health.
期刊最新文献
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