Jonathan A Bernstein, Larry J Wymer, Michael Nye, Stephen J Vesper
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引用次数: 0
摘要
背景:特应性皮炎(AD)是一种因接触过敏原而引起的炎症性皮肤病,估计有 20% 的儿童受到影响。与居住在城市以外地区的儿童相比,城市儿童的特应性皮炎发病率更高。AD 被认为会导致哮喘的发生,是 "特应性进展 "的一部分。目的:我们的目的是确定一个资源匮乏社区中儿童的 AD 与哮喘之间的先后关系。方法在科罗拉多州太阳谷这个资源匮乏的城市社区,我们通过评估 2016 年至 2019 年医疗补助(Medicaid)数据,对 6 岁和 7 岁儿童的 AD 或哮喘诊断进行了研究,以了解 AD 向哮喘发展的过程。研究结果只有 6 岁时的注意力缺失症与 1 年后 7 岁时的哮喘相比,注意力缺失症与哮喘诊断之间的皮尔逊相关性才显著。结论通过研究一个具有一致但混合遗传背景的易感群体,我们发现注意力缺失症和哮喘之间存在顺序和时间上的联系。
The relationship between childhood atopic dermatitis and asthma in an under resourced community.
Background: Atopic dermatitis (AD) is an inflammatory skin disease caused by allergen exposures and estimated to affect ∼20% of children. Children in urban areas have a higher prevalence of AD compared with those living outside of urban areas. AD is believed to lead to asthma development as part of the "atopic march." Objective: Our objective was to determine the sequential and chronological relationships between AD and asthma for children in an under-resourced community. Methods: The progression from AD to asthma in the under-resourced, urban community of Sun Valley, Colorado, was examined by assessing Medicaid data for the years 2016 to 2019 for a diagnosis of AD or asthma in children 6 and 7 years old. Results: Pearson correlations between AD and asthma diagnoses were significant only with respect to AD at age 6 years compared with asthma 1 year later, at age 7 years. Conclusion: By studying a susceptible community with a consistent but mixed genetic background, we found sequential and chronological links between AD and asthma.
期刊介绍:
Allergy & Asthma Proceedings is a peer reviewed publication dedicated to distributing timely scientific research regarding advancements in the knowledge and practice of allergy, asthma and immunology. Its primary readership consists of allergists and pulmonologists. The goal of the Proceedings is to publish articles with a predominantly clinical focus which directly impact quality of care for patients with allergic disease and asthma. Featured topics include asthma, rhinitis, sinusitis, food allergies, allergic skin diseases, diagnostic techniques, allergens, and treatment modalities. Published material includes peer-reviewed original research, clinical trials and review articles.