眼眶粘膜相关淋巴组织(MALT)淋巴瘤是丙型肝炎病毒感染患者的首发症状。

IF 1.1 4区 医学 Q3 OPHTHALMOLOGY Arquivos brasileiros de oftalmologia Pub Date : 2024-03-04 eCollection Date: 2024-01-01 DOI:10.5935/0004-2749.2022-0091
Leyre Lloreda-Martin, Ana Berrocal-Cuadrado, Maria Angeles Torres Nieto, Alicia Galindo-Ferreiro
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引用次数: 0

摘要

12.7%的眼部附件边缘区淋巴瘤可能与丙型肝炎病毒感染有关。我们报告了首例对丙型肝炎病毒药物治疗有反应的眼眶-系统粘膜相关淋巴组织淋巴瘤病例。根据临床、影像学、实验室和组织学检查,一名患有右侧眼眶肿块的 62 岁男性被诊断为 IIA 期眼眶边缘区淋巴瘤,同时感染了丙型肝炎病毒。在接受格列卡韦/匹布伦达韦丙型肝炎病毒治疗一年后,患者全身和眼眶均出现反应。丙型肝炎病毒感染与眼眶-系统粘膜相关淋巴组织淋巴瘤之间存在关联。因此,应评估眼眶粘膜相关淋巴组织淋巴瘤患者的丙型肝炎病毒血清反应性,以用于治疗和预后。
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Orbital mucosa-associated lymphoid tissue (MALT) lymphoma as the initial presentation in patients with hepatitis C virus infection.

Hepatitis C virus infection may be implicated in 12.7% of ocular adnexal marginal zone lymphomas. We present the first case of an orbital-systemic mucosa-associated lymphoid tissue lymphoma that responded to hepatitis C virus medical treatment. A 62-year-old male with a right-sided orbital mass was diagnosed with stage IIA orbital marginal zone lymphoma in addition to hepatitis C virus infection based on clinical, imaging, laboratory, and histological examinations. The systemic and orbital responses were achieved 1 year after undergoing hepatitis C virus treatment with glecaprevir/pibrentasvir. The association between the hepatitis C virus infection and orbital-systemic mucosa-associated lymphoid tissue lymphoma is relevant. Accordingly, patients with orbital mucosa-associated lymphoid tissue lymphoma should be assessed for hepatitis C virus seroreactivity for therapeutic and prognostic purposes.

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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
200
审稿时长
6-12 weeks
期刊介绍: The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.
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