多发性硬化症患者的认知康复计划:试点研究

R.M. Jiménez-Morales , Y. Broche-Pérez , Y. Macías-Delgado , C. Sebrango , S. Díaz-Díaz , R. Castiñeira-Rodriguez , F.J. Pérez-González , C. Forn
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引用次数: 0

摘要

导言近年来,专门针对多发性硬化症(MS)患者认知康复的研究越来越多,但其中很少有研究分析认知储备等变量的影响。本研究旨在探讨认知康复计划的效果,该计划包括认知和身体锻炼的结合,以及改善认知表现、情绪状态和认知储备指数的小组课程。方法将 50 名多发性硬化症患者分为两组:对照组(25 人)和实验组(25 人),对照组进行有氧运动,实验组参加综合认知康复计划(ICRP)。结果与对照组相比,实验组患者的认知功能有所改善,在信息处理速度、注意力、记忆力、认知储备指数和长期情绪方面均有显著变化。
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Cognitive rehabilitation program in patients with multiple sclerosis: A pilot study

Introduction

In recent years, there has been an increase of studies dedicated to cognitive rehabilitation in patients with multiple sclerosis (MS); however, few of these analyze the impact on such variables as cognitive reserve. The study aims to explore the effects of a cognitive rehabilitation program comprising a combination of cognitive and physical exercises, as well as group sessions to improve cognitive performance, emotional state, and cognitive reserve index.

Method

Fifty patients with MS were subdivided into 2 groups: the control group, which performed aerobic exercise (n = 25), and the experimental group (n = 25), which participated in the integrated cognitive rehabilitation program (ICRP). All participants were evaluated 3 times (baseline, post-treatment, and long-term) with the Brief Repeatable Battery of Neuropsychological Tests, Cognitive Reserve Scale, Beck Depression Inventory, and a scale evaluating trait and state anxiety.

Results

Compared with the control group, patients in the experimental group showed improvements in cognitive function, with significant changes in measures of information processing speed, attention, memory, cognitive reserve index, and long-term mood.

Conclusions

The ICRP was effective in improving cognitive and emotional function in MS, and increased the cognitive reserve index.

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