上消化道癌症与基因检测的作用。

IF 2.5 3区 医学 Q2 HEMATOLOGY Hematology-Oncology Clinics of North America Pub Date : 2024-03-07 DOI:10.1016/j.hoc.2024.01.006
Emily C. Harrold MB BCh, BAO, MRCPI , Zsofia K. Stadler MD
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引用次数: 0

摘要

除了少数几种已确定的上消化道癌遗传性癌症综合征外,人们越来越认识到新型致病基因变异(gPVs)对上消化道癌发生的影响。gPVs 的检测对癌症患者的新型治疗方法有潜在影响,对癌症幸存者的监测和降低风险措施也有长期影响,对患者家属也有深远影响。随着多基因组检测的普及,可能会发现新的关联,而种系-体细胞整合对于确定新型 gPV 的真正因果关系至关重要。癌症综合治疗应包括体细胞和种系检测。
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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
86
审稿时长
6-12 weeks
期刊介绍: Hematology/Oncology Clinics updates you on the latest trends in patient management, keeps you up to date on the newest advances, and provides a sound basis for choosing treatment options. Under the direction of an experienced guest editor, each issue focuses on a single topic in hematology and oncology, including hemostasis and thrombosis, molecular and cellular basis of hematology, coagulation disorders, and cancers—bone, gastrointestinal, head and neck, lymphomas, neuroendocrine, breast, renal cell, melanoma, and more.
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