有机体的前景与挑战:从 "人源化 "到 "人源化"。

Wenyan Wang, Yang-Xin Fu
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引用次数: 0

摘要

卡斯滕施密特(Kastenschmidt)等人1 提出了一种突破性的滤泡淋巴瘤类器官培养模型,该模型能够保持 B 细胞和 T 细胞的稳定组成。该模型可用于测试双特异性抗体在激活 T 细胞的同时有效杀伤肿瘤 B 细胞的能力。
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Promises and challenges of organoids: From humanized to human derived.

Kastenschmidt et al.1 present a groundbreaking organoid culture model for follicular lymphoma, which is capable of maintaining stable compositions of B and T cells. This model is utilized in testing bispecific antibodies in effective killing of tumor B cells with the activation of T cells.

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