Ricardo J. Ortega-García, Gaspar Herrera-Aranda, Francisco Rodríguez-Illana, Estaban Figueroa-Martínez, Josefina Álvaro-Vásquez, Roger Juárez-Puc, Janet Mayren-Aguilar
{"title":"肝细胞癌和上消化道出血","authors":"Ricardo J. Ortega-García, Gaspar Herrera-Aranda, Francisco Rodríguez-Illana, Estaban Figueroa-Martínez, Josefina Álvaro-Vásquez, Roger Juárez-Puc, Janet Mayren-Aguilar","doi":"10.1016/j.aohep.2024.101389","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and Objectives</h3><p>Hepatocellular carcinoma represents the most frequent malignant tumor of the liver, being the 5th most frequent cancer in men and the 7th in women worldwide; it is the 3rd cause of death from cancer in the world. To present a case of hepatocellular carcinoma presenting with gastrointestinal bleeding.</p></div><div><h3>Materials and Patients</h3><p>A 39-year-old female began her condition two days ago with the presence of hematemesis, accompanied by nausea, asthenia, and adynamia. On examination, icteric conjunctivae, globose abdomen, with the presence of abdominal distension, grade I ascites. Edema in the lower limbs +. Liver ultrasound with liver nodular lesions, chronic lithiasic cholecystitis, and free fluid in the abdominopelvic cavity. A simple and contrasted CT scan of the abdomen is requested with the presence of tumor activity at the level of the liver, portal thrombosis, free fluid in the abdominal cavity, and marginal T12-L1 osteocytes.</p></div><div><h3>Results</h3><p>We proceeded to perform sclerotherapy of esophageal varices and ligatures. Later, alpha-fetoprotein was requested, which reports 3680 ng/ml. The diagnosis of hepatocarcinoma was established and he was referred to the oncology service.</p></div><div><h3>Conclusions</h3><p>The best results are obtained with multidisciplinary teams for the diagnosis and treatment of this disease.</p></div>","PeriodicalId":7979,"journal":{"name":"Annals of hepatology","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1665268124001832/pdfft?md5=86f5ba3ca82541a89b5d1f4f04c51eb5&pid=1-s2.0-S1665268124001832-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Hepatocellular carcinoma and upper gastrointestinal bleeding\",\"authors\":\"Ricardo J. Ortega-García, Gaspar Herrera-Aranda, Francisco Rodríguez-Illana, Estaban Figueroa-Martínez, Josefina Álvaro-Vásquez, Roger Juárez-Puc, Janet Mayren-Aguilar\",\"doi\":\"10.1016/j.aohep.2024.101389\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction and Objectives</h3><p>Hepatocellular carcinoma represents the most frequent malignant tumor of the liver, being the 5th most frequent cancer in men and the 7th in women worldwide; it is the 3rd cause of death from cancer in the world. To present a case of hepatocellular carcinoma presenting with gastrointestinal bleeding.</p></div><div><h3>Materials and Patients</h3><p>A 39-year-old female began her condition two days ago with the presence of hematemesis, accompanied by nausea, asthenia, and adynamia. On examination, icteric conjunctivae, globose abdomen, with the presence of abdominal distension, grade I ascites. Edema in the lower limbs +. Liver ultrasound with liver nodular lesions, chronic lithiasic cholecystitis, and free fluid in the abdominopelvic cavity. A simple and contrasted CT scan of the abdomen is requested with the presence of tumor activity at the level of the liver, portal thrombosis, free fluid in the abdominal cavity, and marginal T12-L1 osteocytes.</p></div><div><h3>Results</h3><p>We proceeded to perform sclerotherapy of esophageal varices and ligatures. Later, alpha-fetoprotein was requested, which reports 3680 ng/ml. The diagnosis of hepatocarcinoma was established and he was referred to the oncology service.</p></div><div><h3>Conclusions</h3><p>The best results are obtained with multidisciplinary teams for the diagnosis and treatment of this disease.</p></div>\",\"PeriodicalId\":7979,\"journal\":{\"name\":\"Annals of hepatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1665268124001832/pdfft?md5=86f5ba3ca82541a89b5d1f4f04c51eb5&pid=1-s2.0-S1665268124001832-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of hepatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1665268124001832\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of hepatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1665268124001832","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
Hepatocellular carcinoma and upper gastrointestinal bleeding
Introduction and Objectives
Hepatocellular carcinoma represents the most frequent malignant tumor of the liver, being the 5th most frequent cancer in men and the 7th in women worldwide; it is the 3rd cause of death from cancer in the world. To present a case of hepatocellular carcinoma presenting with gastrointestinal bleeding.
Materials and Patients
A 39-year-old female began her condition two days ago with the presence of hematemesis, accompanied by nausea, asthenia, and adynamia. On examination, icteric conjunctivae, globose abdomen, with the presence of abdominal distension, grade I ascites. Edema in the lower limbs +. Liver ultrasound with liver nodular lesions, chronic lithiasic cholecystitis, and free fluid in the abdominopelvic cavity. A simple and contrasted CT scan of the abdomen is requested with the presence of tumor activity at the level of the liver, portal thrombosis, free fluid in the abdominal cavity, and marginal T12-L1 osteocytes.
Results
We proceeded to perform sclerotherapy of esophageal varices and ligatures. Later, alpha-fetoprotein was requested, which reports 3680 ng/ml. The diagnosis of hepatocarcinoma was established and he was referred to the oncology service.
Conclusions
The best results are obtained with multidisciplinary teams for the diagnosis and treatment of this disease.
期刊介绍:
Annals of Hepatology publishes original research on the biology and diseases of the liver in both humans and experimental models. Contributions may be submitted as regular articles. The journal also publishes concise reviews of both basic and clinical topics.