{"title":"食用皮纳林继发肝炎","authors":"Leslie Moranchel–García , Eduardo Vilchis–Chaparro","doi":"10.1016/j.aohep.2024.101447","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction and Objectives</h3><p>The use of natural products without proper assessment is common and favored by the popularity of phytotherapeutics. The regulations related to the prescription and use of these products are scarce, which leads to their being widely used in self-medication. We present the clinical case of a woman who consumed piñalim and presented hepatotoxicity</p></div><div><h3>Materials and Patients</h3><p>A 29-year-old woman without significant history. She was admitted to the general surgery service for cholecystectomy. After preoperative evaluation, abnormalities in liver function tests (LFT) stood out, for which reason they intentionally asked about the consumption of alcohol, drugs, supplements or herbal and/or homeopathic products, referring to the daily consumption during the last year of PIÑALIM (red, green and white tea) in order to lose weight. Ultrasound of the liver and bile ducts reported: liver of normal shape, size and situation, with no evidence of solid or cystic lesions. Bile duct without dilatation. Gallbladder with a 5.6mm thick wall, without images suggestive of stones. The surgical report showed a lack of findings in the gallbladder and liver. The jaundice and altered LFT persisted in the postoperative period (mixed pattern); additional tests were performed: HBV-HCV-HAV-HIV viral panel: TORCH negative. Negative Tomography of the abdomen without relevant findings. ANA: Negative Until now, the only hepatotoxic agent identified (PIÑALIM) had already been suspended, so this behavior was maintained, avoiding the consumption of any drug. In the following control, the LFT maintained a downward trend, until normalizing 6 months after the definitive suspension of the infusion. (Table 1)</p></div><div><h3>Results</h3><p>After the definitive suspension of the tea, the LFT were normalized, thus concluding the direct relationship of the product by having a score on the CIOM/RUCAM scale of 9 (definitive cause of hepatotoxicity).</p></div><div><h3>Conclusions</h3><p>The report of hepatitis associated with infusions is becoming more frequent, it is important to raise awareness about our patients in the \"non-safety\" of natural products and in the medical team to alert about these products and avoid procedures unnecessary surgeries.</p></div>","PeriodicalId":7979,"journal":{"name":"Annals of hepatology","volume":null,"pages":null},"PeriodicalIF":3.7000,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1665268124002412/pdfft?md5=e13b39a7f9b3717f54918915909a8ea8&pid=1-s2.0-S1665268124002412-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Hepatitis secondary to consumption of piñalim\",\"authors\":\"Leslie Moranchel–García , Eduardo Vilchis–Chaparro\",\"doi\":\"10.1016/j.aohep.2024.101447\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction and Objectives</h3><p>The use of natural products without proper assessment is common and favored by the popularity of phytotherapeutics. The regulations related to the prescription and use of these products are scarce, which leads to their being widely used in self-medication. We present the clinical case of a woman who consumed piñalim and presented hepatotoxicity</p></div><div><h3>Materials and Patients</h3><p>A 29-year-old woman without significant history. She was admitted to the general surgery service for cholecystectomy. After preoperative evaluation, abnormalities in liver function tests (LFT) stood out, for which reason they intentionally asked about the consumption of alcohol, drugs, supplements or herbal and/or homeopathic products, referring to the daily consumption during the last year of PIÑALIM (red, green and white tea) in order to lose weight. Ultrasound of the liver and bile ducts reported: liver of normal shape, size and situation, with no evidence of solid or cystic lesions. Bile duct without dilatation. Gallbladder with a 5.6mm thick wall, without images suggestive of stones. The surgical report showed a lack of findings in the gallbladder and liver. The jaundice and altered LFT persisted in the postoperative period (mixed pattern); additional tests were performed: HBV-HCV-HAV-HIV viral panel: TORCH negative. Negative Tomography of the abdomen without relevant findings. ANA: Negative Until now, the only hepatotoxic agent identified (PIÑALIM) had already been suspended, so this behavior was maintained, avoiding the consumption of any drug. In the following control, the LFT maintained a downward trend, until normalizing 6 months after the definitive suspension of the infusion. (Table 1)</p></div><div><h3>Results</h3><p>After the definitive suspension of the tea, the LFT were normalized, thus concluding the direct relationship of the product by having a score on the CIOM/RUCAM scale of 9 (definitive cause of hepatotoxicity).</p></div><div><h3>Conclusions</h3><p>The report of hepatitis associated with infusions is becoming more frequent, it is important to raise awareness about our patients in the \\\"non-safety\\\" of natural products and in the medical team to alert about these products and avoid procedures unnecessary surgeries.</p></div>\",\"PeriodicalId\":7979,\"journal\":{\"name\":\"Annals of hepatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.7000,\"publicationDate\":\"2024-02-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S1665268124002412/pdfft?md5=e13b39a7f9b3717f54918915909a8ea8&pid=1-s2.0-S1665268124002412-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annals of hepatology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1665268124002412\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"GASTROENTEROLOGY & HEPATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of hepatology","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1665268124002412","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
The use of natural products without proper assessment is common and favored by the popularity of phytotherapeutics. The regulations related to the prescription and use of these products are scarce, which leads to their being widely used in self-medication. We present the clinical case of a woman who consumed piñalim and presented hepatotoxicity
Materials and Patients
A 29-year-old woman without significant history. She was admitted to the general surgery service for cholecystectomy. After preoperative evaluation, abnormalities in liver function tests (LFT) stood out, for which reason they intentionally asked about the consumption of alcohol, drugs, supplements or herbal and/or homeopathic products, referring to the daily consumption during the last year of PIÑALIM (red, green and white tea) in order to lose weight. Ultrasound of the liver and bile ducts reported: liver of normal shape, size and situation, with no evidence of solid or cystic lesions. Bile duct without dilatation. Gallbladder with a 5.6mm thick wall, without images suggestive of stones. The surgical report showed a lack of findings in the gallbladder and liver. The jaundice and altered LFT persisted in the postoperative period (mixed pattern); additional tests were performed: HBV-HCV-HAV-HIV viral panel: TORCH negative. Negative Tomography of the abdomen without relevant findings. ANA: Negative Until now, the only hepatotoxic agent identified (PIÑALIM) had already been suspended, so this behavior was maintained, avoiding the consumption of any drug. In the following control, the LFT maintained a downward trend, until normalizing 6 months after the definitive suspension of the infusion. (Table 1)
Results
After the definitive suspension of the tea, the LFT were normalized, thus concluding the direct relationship of the product by having a score on the CIOM/RUCAM scale of 9 (definitive cause of hepatotoxicity).
Conclusions
The report of hepatitis associated with infusions is becoming more frequent, it is important to raise awareness about our patients in the "non-safety" of natural products and in the medical team to alert about these products and avoid procedures unnecessary surgeries.
期刊介绍:
Annals of Hepatology publishes original research on the biology and diseases of the liver in both humans and experimental models. Contributions may be submitted as regular articles. The journal also publishes concise reviews of both basic and clinical topics.