降低心血管疾病风险和改变生活方式:患者反应的横断面分析。

Q4 Agricultural and Biological Sciences Journal of Advanced Zoology Pub Date : 2024-03-05 DOI:10.53555/jaz.v45i3.3749
S. T, Maheshkumar V P, J. S
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引用次数: 0

摘要

随着总胆固醇和低密度脂蛋白胆固醇水平的降低,心血管事件风险也随之降低,这被称为 "胆固醇悖论 "或 "风险因素逆转"。心血管风险与低密度脂蛋白胆固醇水平之间并不存在线性关系,而心血管事件的其他重要风险因素却被忽视了。这项研究的目的是,除了那些已被证实会导致血脂异常的因素外,找出心血管事件的其他可改变的风险因素。一项横断面研究在一家三级医院对 652 名参与者进行了调查。根据心血管事件病史将患者分为两组。通过预先验证的调查问卷对人口统计学和患者回答进行了分析。通过静脉穿刺采集了 5 毫升血液样本,并对血脂概况进行了估计。心血管事件与解释性变量之间的关系采用卡方检验(Chi Square test)和95%置信区间的比值比(Odds ratio)来确定。吸烟者发生心血管事件的风险较高,为 0.232 [0.144 - 0.373]。食用白糖、精炼油、加工冷饮和快餐产品分别会增加心血管疾病的风险。此外,在对患者进行一年的咨询后,发现总胆固醇、低密度脂蛋白胆固醇和甘油三酯均有所下降。血脂异常诱发动脉粥样硬化的经典假说可能并不是冠心病事件的主要原因。在此,我们报告了高脂肪饮食与心血管疾病风险之间没有关联,但我们观察到精制和超加工食品消费者的风险较高。然而,在转向食用非精制食品的患者中,胆固醇得到了明显控制。
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Cardiovascular Diseases Risk Reduction And Lifestyle Modification:Cross Sectional Ansalysis Of Patient Responses.
A decrease in cardiovascular event risk with a decrease in total and LDL – cholesterol level is termed as “cholesterol paradox” or “risk factor reversal”. Cardiovascular risk does not have a linear relationship between LDL – cholesterol levels, and other substantial risk factors of cardiovascular events are being disregarded.The aim of this study is, to identify modifiable risk factors of cardiovascular events other than those well proved to cause dyslipidemia. A cross-sectional study was conducted with 652 participants in a tertiary care hospital. Patients were grouped into two, based on the history of cardiovascular events. Demographics and patient responses captured using pre-validated questionnaires were analyzed. 5mL blood samples were collected by venipuncture and lipid profile was estimated. Association between cardiovascular events and explanatory variables. was determined using Chi square test and Odds ratio at 95% confidence intervals. Higher risk of CV events was found among smokers 0.232 [0.144 – 0.373]. Consumption of white sugar, refined oil, processed cold beverages and fast food products increased CV risk respectively. Moreover, total cholesterol, LDL-C and triglycerides were found to decrease after one year of counselling the patients. The classical hypothesis of dyslipidemia induced atherosclerosis may not be the predominant cause of CV events. Herein, we report no association between high fat diet and CV risk while we observed higher risk in consumers of refined and ultra processed food products. However, significant control of cholesterol was observed in patients who shifted to Unrefined food products.
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来源期刊
Journal of Advanced Zoology
Journal of Advanced Zoology Agricultural and Biological Sciences-Animal Science and Zoology
自引率
0.00%
发文量
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期刊介绍: The Journal of Advanced Zoology started in 1980 is a peer reviewed half yearly online and prints journal, issued in June and December devoted to the publication of original research work in the various disciplines of Zoology.
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