心内血栓,原发灶不明的转移性癌症的不寻常表现:病例报告

IF 0.3 Q4 SURGERY Cirugia Cardiovascular Pub Date : 2024-03-01 DOI:10.1016/j.circv.2023.09.002
Miguel Q. Clemente-Afonso , Yiliam Blanco-Pérez , Angela M. Castro-Arca , Hashem N. Sari-DarDeek , Yasser Colao-Jiménez
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引用次数: 0

摘要

右心房血栓伴上腔静脉阻塞作为原发灶不明的转移癌的初始表现并不常见。以证据为基础的血栓患者临床治疗指南仍然有限。我们为大家介绍一位 82 岁的患者,他有慢性阻塞性肺病和糖尿病病史,并且已戒烟,因频繁晕厥和局限性呼吸困难而入院。超声心动图检查显示,患者右心房上腔静脉入口处有一巨大肿块。手术切除了该肿块,结果发现是一个血栓,还切除了前纵隔的一个淋巴结,结果显示转移性未分化大细胞癌阳性。在进行的研究中没有发现原发病灶。术后四个月,患者的临床症状仍然稳定,只是有轻微的呼吸困难。然而,这样诊断的患者预后很差。在对阻塞性心内血栓进行手术时,应怀疑邻近的副肿瘤综合征的可能性,因此在临床实践中应考虑到这一点,并在手术过程中收集好样本,以便进行解剖病理学研究。手术治疗尽管有一定风险,但对于心内肿块并伴有血流动力学损害的患者来说,手术治疗不失为一种选择。
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Trombo intracardiaco, presentación inusual del carcinoma metastásico con primario desconocido: reporte de un caso

Right atrial thrombus with superior vena cava obstruction as the initial manifestation of metastatic carcinoma of unknown primary origin is not a frequent event. Evidence-based guidelines for the clinical management of patients with thrombus are still limited. We present an 82-year-old patient with a history of COPD, diabetes mellitus and an ex-smoker, who was admitted due to frequent syncope and limiting dyspnea. The echocardiographic study revealed a large mass in the right atrium at the entrance of the superior vena cava. Surgical resection of the same was performed, which turned out to be a thrombus, a lymph node in the anterior mediastinum was also resected, which was positive for metastatic undifferentiated large cell carcinoma. The primary lesion was not found in the studies carried out. The patient remains stable clinically with mild dyspnea four months after surgery. However, the prognosis for a patient with such a diagnosis is poor. In the operation of an obstructive intracardiac thrombus, the possibility of an adjacent paraneoplastic syndrome should be suspected, so it should be taken into account in clinical practice and a good collection of samples should be made in the surgical act for the anatomopathological study. Surgery, despite being risky, is an option in patients with an intracardiac mass with hemodynamic compromise

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来源期刊
CiteScore
0.50
自引率
66.70%
发文量
109
审稿时长
69 days
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