长达十年的洞察力:追踪意大利巴勒莫曾接触石棉的工人中与石棉相关的健康影响。

IF 1.5 Q3 HEALTH CARE SCIENCES & SERVICES Annali di igiene : medicina preventiva e di comunita Pub Date : 2024-09-01 Epub Date: 2024-03-07 DOI:10.7416/ai.2024.2619
Claudio Costantino, Caterina Ledda, Matteo Riccò, Eduardo Costagliola, Francesco Balsamo, Miriam Belluzzo, Nicole Bonaccorso, Alessandro Carubia, Luciano D'Azzo, Martina Sciortino, Tania Vitello, Luigi Zagra, Santo Fruscione, Sara Ilardo, Elisa Trapani, Giuseppe Calamusa, Venerando Rapisarda, Walter Mazzucco
{"title":"长达十年的洞察力:追踪意大利巴勒莫曾接触石棉的工人中与石棉相关的健康影响。","authors":"Claudio Costantino, Caterina Ledda, Matteo Riccò, Eduardo Costagliola, Francesco Balsamo, Miriam Belluzzo, Nicole Bonaccorso, Alessandro Carubia, Luciano D'Azzo, Martina Sciortino, Tania Vitello, Luigi Zagra, Santo Fruscione, Sara Ilardo, Elisa Trapani, Giuseppe Calamusa, Venerando Rapisarda, Walter Mazzucco","doi":"10.7416/ai.2024.2619","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Asbestos is a foremost occupational carcinogen globally. Despite the prohibition under Law 257/1992, Italy persists as one of the European nations most burdened by asbestos-related diseases (ARDs). This research assessed ARD cases in asbestos-exposed workers from the Province of Palermo, Italy, spanning 2010-2021.</p><p><strong>Methods: </strong>Data acquisition utilized the epidemiological dataset from the 'Service of Prevention and Safety on Work Environment' under the Prevention Department of Palermo's Local Health Authority (LHA).</p><p><strong>Results: </strong>Between 2010 and 2021, we identified 245 ARD instances, comprising 163 Asbestosis/Pleural plaques, 41 Lung Cancers, 38 Mesotheliomas, and 3 unspecified cases. Multivariate analysis indicated a notable decline in temporal exposure for mesothelioma (HR=0.933; 95% CI=0.902-0.965) and lung cancer (HR=0.93; 95% CI=0.90-0.978) relative to pleural plaques/asbestosis. Tobacco use displayed a pronounced correlation with lung cancer (smoker HR=64.520 95% CI=13,075-318.390; former smoker HR=20.917 95% CI=4,913-89.048). A significant link was observed between mesothelioma and pleural plaques/asbestosis in those employed in shipbuilding and repair (HR=0.371 95% CI=0.155-0.892).</p><p><strong>Conclusions: </strong>ARDs persist in clinical observations, even following the 1992 cessation of asbestos-related activities, emphasizing an enduring public health challenge. Enhancing prevention strategies is paramount, focusing on amplifying anamnestic and occupational data collection, thereby facilitating superior early diagnosis strategies for these maladies in the occupationally exposed cohort.</p>","PeriodicalId":7999,"journal":{"name":"Annali di igiene : medicina preventiva e di comunita","volume":null,"pages":null},"PeriodicalIF":1.5000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Decade-long insights: tracking asbestos-related health impacts among formerly exposed workers in Palermo, Italy.\",\"authors\":\"Claudio Costantino, Caterina Ledda, Matteo Riccò, Eduardo Costagliola, Francesco Balsamo, Miriam Belluzzo, Nicole Bonaccorso, Alessandro Carubia, Luciano D'Azzo, Martina Sciortino, Tania Vitello, Luigi Zagra, Santo Fruscione, Sara Ilardo, Elisa Trapani, Giuseppe Calamusa, Venerando Rapisarda, Walter Mazzucco\",\"doi\":\"10.7416/ai.2024.2619\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Asbestos is a foremost occupational carcinogen globally. Despite the prohibition under Law 257/1992, Italy persists as one of the European nations most burdened by asbestos-related diseases (ARDs). This research assessed ARD cases in asbestos-exposed workers from the Province of Palermo, Italy, spanning 2010-2021.</p><p><strong>Methods: </strong>Data acquisition utilized the epidemiological dataset from the 'Service of Prevention and Safety on Work Environment' under the Prevention Department of Palermo's Local Health Authority (LHA).</p><p><strong>Results: </strong>Between 2010 and 2021, we identified 245 ARD instances, comprising 163 Asbestosis/Pleural plaques, 41 Lung Cancers, 38 Mesotheliomas, and 3 unspecified cases. Multivariate analysis indicated a notable decline in temporal exposure for mesothelioma (HR=0.933; 95% CI=0.902-0.965) and lung cancer (HR=0.93; 95% CI=0.90-0.978) relative to pleural plaques/asbestosis. Tobacco use displayed a pronounced correlation with lung cancer (smoker HR=64.520 95% CI=13,075-318.390; former smoker HR=20.917 95% CI=4,913-89.048). A significant link was observed between mesothelioma and pleural plaques/asbestosis in those employed in shipbuilding and repair (HR=0.371 95% CI=0.155-0.892).</p><p><strong>Conclusions: </strong>ARDs persist in clinical observations, even following the 1992 cessation of asbestos-related activities, emphasizing an enduring public health challenge. Enhancing prevention strategies is paramount, focusing on amplifying anamnestic and occupational data collection, thereby facilitating superior early diagnosis strategies for these maladies in the occupationally exposed cohort.</p>\",\"PeriodicalId\":7999,\"journal\":{\"name\":\"Annali di igiene : medicina preventiva e di comunita\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.5000,\"publicationDate\":\"2024-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Annali di igiene : medicina preventiva e di comunita\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.7416/ai.2024.2619\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/3/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"HEALTH CARE SCIENCES & SERVICES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annali di igiene : medicina preventiva e di comunita","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7416/ai.2024.2619","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/3/7 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"HEALTH CARE SCIENCES & SERVICES","Score":null,"Total":0}
引用次数: 0

摘要

背景:石棉是全球最主要的职业致癌物。尽管第 257/1992 号法律禁止使用石棉,但意大利仍然是欧洲国家中患石棉相关疾病(ARDs)最多的国家之一。这项研究评估了 2010-2021 年期间意大利巴勒莫省接触石棉工人的 ARD 病例:数据采集利用了巴勒莫地方卫生局(LHA)预防部下属的 "工作环境预防和安全服务 "的流行病学数据集:结果:2010 年至 2021 年间,我们共发现了 245 例急性放射损伤病例,其中包括 163 例石棉沉滞症/胸膜斑、41 例肺癌、38 例间皮瘤和 3 例不明病例。多变量分析表明,相对于胸膜斑块/石棉沉着病,间皮瘤(HR=0.933;95% CI=0.902-0.965)和肺癌(HR=0.93;95% CI=0.90-0.978)的时间暴露显著下降。吸烟与肺癌有明显的相关性(吸烟者 HR=64.520 95% CI=13,075-318.390;曾经吸烟者 HR=20.917 95% CI=4,913-89.048)。在受雇于造船和修船业的人群中,间皮瘤与胸膜斑块/石棉沉着病之间存在明显联系(HR=0.371 95% CI=0.155-0.892):结论:即使在 1992 年停止与石棉有关的活动之后,ARD 在临床观察中依然存在,这凸显了公共卫生面临的持久挑战。加强预防策略至关重要,重点是扩大异常和职业数据的收集,从而促进对职业暴露人群中这些疾病的早期诊断策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Decade-long insights: tracking asbestos-related health impacts among formerly exposed workers in Palermo, Italy.

Background: Asbestos is a foremost occupational carcinogen globally. Despite the prohibition under Law 257/1992, Italy persists as one of the European nations most burdened by asbestos-related diseases (ARDs). This research assessed ARD cases in asbestos-exposed workers from the Province of Palermo, Italy, spanning 2010-2021.

Methods: Data acquisition utilized the epidemiological dataset from the 'Service of Prevention and Safety on Work Environment' under the Prevention Department of Palermo's Local Health Authority (LHA).

Results: Between 2010 and 2021, we identified 245 ARD instances, comprising 163 Asbestosis/Pleural plaques, 41 Lung Cancers, 38 Mesotheliomas, and 3 unspecified cases. Multivariate analysis indicated a notable decline in temporal exposure for mesothelioma (HR=0.933; 95% CI=0.902-0.965) and lung cancer (HR=0.93; 95% CI=0.90-0.978) relative to pleural plaques/asbestosis. Tobacco use displayed a pronounced correlation with lung cancer (smoker HR=64.520 95% CI=13,075-318.390; former smoker HR=20.917 95% CI=4,913-89.048). A significant link was observed between mesothelioma and pleural plaques/asbestosis in those employed in shipbuilding and repair (HR=0.371 95% CI=0.155-0.892).

Conclusions: ARDs persist in clinical observations, even following the 1992 cessation of asbestos-related activities, emphasizing an enduring public health challenge. Enhancing prevention strategies is paramount, focusing on amplifying anamnestic and occupational data collection, thereby facilitating superior early diagnosis strategies for these maladies in the occupationally exposed cohort.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Annali di igiene : medicina preventiva e di comunita
Annali di igiene : medicina preventiva e di comunita HEALTH CARE SCIENCES & SERVICES-
CiteScore
3.40
自引率
0.00%
发文量
69
期刊最新文献
Intentions to move abroad among medical students: a cross-sectional study to investigate determinants and opinions. Prevalence and predictors of hand hygiene compliance in clinical, surgical and intensive care unit wards: results of a second cross-sectional study at the Umberto I teaching hospital of Rome. The prevention of medication errors in the home care setting: a scoping review. Training in infection prevention and control: survey on the volume and on the learning demands of healthcare-associated infections control figures in the Emilia-Romagna Region (Northern Italy). Machine learning vs. regression models to predict the risk of Legionella contamination in a hospital water network.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1