小儿颅脑损伤的上矢状窦血栓切除术

IF 0.9 4区 医学 Q4 CLINICAL NEUROLOGY Pediatric Neurosurgery Pub Date : 2024-01-01 Epub Date: 2024-03-12 DOI:10.1159/000538184
Phillip Mitchell Johansen, Bronson Ciavarra, Ryan McCormack, Matthew Kole, Gary Spiegel, Stephen Alan Fletcher
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引用次数: 0

摘要

简介:闭合性颅脑损伤可继发于各种不同机制的脑静脉窦损伤和随后的血栓形成。颅骨骨折可撕裂或以其他方式破坏邻近的硬脑膜窦。此类损伤的后遗症可能包括血栓形成以及静脉窦部分或完全闭塞,最终导致静脉严重充血。矢状窦损伤的后果更为严重,因为血流必须流入矢状窦,尤其是在冠状缝后方。在这种情况下,静脉梗塞可能是头部受伤的一种严重并危及生命的并发症:病例介绍:一名 2 岁女性患者因颅骨中线附近凹陷性骨折和矢状窦血栓而就诊。抗凝是治疗脑静脉窦血栓的标准方法,但因颅内出血而禁用,因此立即进行了血栓切除术,随访 9 个月后神经功能成功恢复。据我们所知,该病例是因外伤导致上矢状窦血栓形成而接受机械性血栓切除术的最年轻患者:结论:小儿闭合性颅脑损伤可能与 CVST 相关,导致静脉引流受阻和严重的神经系统后遗症。与自发性脑静脉窦血栓形成(CVST)的成人患者不同,抗凝是治疗的标准,而外伤性 CVST 的儿科患者可能有抗凝禁忌症。如果患者有颅内出血等抗凝禁忌症,由经验丰富的神经介入专家进行血管内机械性血栓切除术可能是一种有效的干预方法。
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Superior Sagittal Sinus Thrombectomy in Pediatric Head Injury.

Introduction: Injury and subsequent thrombosis of the cerebral venous sinuses may be caused by closed head injuries secondary to a variety of different mechanisms. Skull fractures can lacerate or otherwise disrupt adjacent dural sinuses. The sequelae of such injuries may include thrombosis and either partial or total occlusion of the sinus, ultimately resulting in significant venous congestion. Sagittal sinus injury is associated with a more serious outcome due to the obligatory flow into the sinus, especially posterior to the coronal suture. In such cases, venous infarction may be a severe and life-threatening complication of head injury.

Case presentation: A 2-year-old female presented with a depressed skull fracture near the midline and a thrombus in the sagittal sinus. Anticoagulation, the standard treatment cerebral venous sinus thrombosis (CVST), was contraindicated due to intracranial hemorrhage, so immediate thrombectomy was performed with successful neurologic recovery at 9-month follow-up. To our knowledge, this case is the youngest patient documented to receive mechanical thrombectomy for superior sagittal sinus (SSS) thrombosis due to trauma.

Conclusion: Closed head injuries in pediatric patients may be associated with CVST, with resulting venous drainage compromise and profound neurologic sequelae. Unlike adult patients with spontaneous CVST in which anticoagulation are the standard of care, pediatric patients experiencing traumatic CVST may have contraindications to anticoagulants. If the patient has a contraindication to anticoagulation such as intracranial bleeding, endovascular mechanical thrombectomy may be an effective intervention when performed by an experienced neurointerventionalist.

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来源期刊
Pediatric Neurosurgery
Pediatric Neurosurgery 医学-临床神经学
CiteScore
1.30
自引率
0.00%
发文量
45
审稿时长
>12 weeks
期刊介绍: Articles in ''Pediatric Neurosurgery'' strives to publish new information and observations in pediatric neurosurgery and the allied fields of neurology, neuroradiology and neuropathology as they relate to the etiology of neurologic diseases and the operative care of affected patients. In addition to experimental and clinical studies, the journal presents critical reviews which provide the reader with an update on selected topics as well as case histories and reports on advances in methodology and technique. This thought-provoking focus encourages dissemination of information from neurosurgeons and neuroscientists around the world that will be of interest to clinicians and researchers concerned with pediatric, congenital, and developmental diseases of the nervous system.
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