[2004年至2010年伊格纳西奥-查韦斯国家心脏病研究所恰加斯病血清阳性反应率]。

Diana V Reséndiz-Solís, Alejandro Ruiz-Sánchez, Martha A Ballinas-Verdugo
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引用次数: 0

摘要

背景:不同的病原体可导致扩张型心肌病,其中一种是克鲁斯原虫。克鲁兹锥虫慢性感染会导致慢性南美锥虫病心肌病,并影响窦房结和 His 束以下的传导系统;此外,由于室性心律失常,它还显示出极好的致心律失常潜能。了解临床特征和进行血清学检测对诊断慢性南美锥虫病心肌病至关重要。寻找抗体的血清学诊断是以阶段为基础的,它可以预测扩张型心肌病的发展:本研究的目的是描述血清学检查结果为柯萨奇病毒阳性的患者发生扩张型心肌病的频率:方法:共对 961 名经医学和临床诊断为扩张型心肌病的患者进行了研究。其中,128 人被诊断为慢性南美锥虫病心肌病,并在两种血清学检测中发现 T. cruzi 血清学阳性:临床结果来自心电图结果和患者的临床病史:总之,希氏束右支完全阻塞(44.2%)是所研究患者的主要传导障碍之一。在血清流行率方面,14%被诊断为扩张型心肌病的患者体内有抗克鲁兹疟原虫抗体。
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[Seroprevalence of Chagas disease at the Instituto Nacional de Cardiología Ignacio Chávez from 2004 to 2010].

Background: Different pathogens can cause dilated cardiomyopathy, one of them is Trypanosoma cruzi protozoan. T.cruzi-chronic infection causes chronic Chagasic cardiomyopathy and affects the sinus node and the conduction systembelow the bundle of His; besides, it shows excellent arrhythmogenic potential because of ventricular arrhythmias. Knowingthe clinical characteristics and performing serological tests to diagnose chronic Chagasic cardiomyopathy is essential. The serological diagnosis for searching the antibodies is based on the phase, which can be a predictor for the development of dilated cardiomyopathy.

Objectives: In this work, the objective was to describe the frequency of dilated cardiomyopathy in patients with T. cruzi positive serology.

Method: A total of 961 patients who were medically and clinically diagnosed with dilated cardiomyopathy were studied. Of these, 128 were diagnosed with chronic Chagasic cardiomyopathy and had positive serology for T. cruzi with two serological tests.

Results: The clinical findings were obtained from the results of the electrocardiograms and were taken from the patient's clinical histories.

Conclusion: In conclusion, complete blockage of the right branch of the bundle of His (44.2%) is one of the primary conduction disorders in the patients studied. Regarding seroprevalence, 14% of patients diagnosed with dilated cardiomyopathy had anti-T. cruzi antibodies.

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