[黄疽性肾上腺炎:肾上腺肿瘤罕见且难以鉴别诊断的疾病]。

Pathologie (Heidelberg, Germany) Pub Date : 2024-05-01 Epub Date: 2024-03-12 DOI:10.1007/s00292-024-01312-x
Wolfgang Saeger, Andreas M Luebke, S T Mekoula, Jörg-Michael Pahnke
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引用次数: 0

摘要

一名发烧约 39 摄氏度的 29 岁女性经放射学诊断患有肿瘤,因怀疑是胆囊炎或肝脓肿而接受了手术。在肾上腺中发现了一个实体瘤,并将其切除。冰冻切片结果显示,实体瘤的诊断和归属并不明确。组织学检查发现,肿瘤由密集成团的大组织细胞样细胞组成,表达波形蛋白、CD68和CD163,角蛋白、langerin和SMA阴性。我们诊断为黄疽性肾上腺炎,并讨论了鉴别诊断(朗格汉斯细胞组织细胞增生症、罗赛-多夫曼病、恶性肿瘤、埃尔德海姆-切斯特病)。
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[Xanthogranulomatous adrenalitis : A rare and difficult differential diagnosis of adrenal gland tumors].

A radiologically diagnosed tumor in a 29-year-old woman with a fever of around 39 °C was operated on under the suspicion of cholecystitis or a liver abscess. A solid tumor was found in the adrenal gland and resected. The frozen section findings did not reveal a clear diagnosis of entity and assignment. Histologically, the tumor was found to consist of densely clustered large histiocyte-like cells with expression of vimentin, CD68, and CD163 as well as negativity for keratin, langerin, and SMA. We diagnosed xanthogranulomatous adrenalitis and discussed the differential diagnoses (Langerhans cell histiocytosis, Rosai-Dorfman disease, malakoplakia, Erdheim-Chester disease).

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