角膜塑形镜和正常眼的金字塔形像差计测量的重复性。

IF 2.6 3区 医学 Q2 OPHTHALMOLOGY Journal of cataract and refractive surgery Pub Date : 2024-07-01 DOI:10.1097/j.jcrs.0000000000001443
Perla Ibrahim, Jad F Assaf, Romy Bejjani, Julien Torbey, Madeleine Yehia, Saleh Bahir Al-Ulloom, Shady T Awwad
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引用次数: 0

摘要

目的:评估角膜塑形镜和正常眼样本中锥体外差计测量的受试者内重复性:贝鲁特美国大学医学中心,黎巴嫩贝鲁特:设计:前瞻性重复性比较分析:研究对象:角膜炎患者和正常眼:观察程序:每只眼睛连续拍摄 3 次:主要结果测量:评估不同眼球高阶和低阶像差(分别为 HOAs 和 LOAs)的可重复性,以及低至五阶的 Zernike 系数。重复性通过受试者内标准偏差(Sw)、重复性限值(r)和类内相关系数(ICC)等参数进行评估:共纳入 72 名角膜塑形镜患者(72 只眼)和 76 名正常患者(76 只眼)。在正常眼和角膜病患者眼中,总LOA和HOA以及每个Zernike系数的ICC均大于0.9。平均最大角膜度数(Kmax)=50D的角膜塑形眼的Sw.1级角膜病和HOA2D的重复性也有类似的改善趋势:结论:由高清锥形像差仪生成的眼像差测量值在正常眼和轻度角膜病眼中都具有较高的重复性;在晚期角膜病中具有中等重复性,但临床上仍可接受。这对于眼波前引导治疗尤为重要。
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Repeatability of pyramidal aberrometer measurements in keratoconus and normal eyes.

Purpose: To evaluate the intrasubject repeatability of pyramidal aberrometer measurements in a sample of keratoconus and normal eyes.

Setting: American University of Beirut Medical Center, Beirut, Lebanon.

Design: Prospective comparative repeatability analysis.

Methods: Study population: Keratoconus and normal eyes from adult patients. Observation procedures: Each eye was evaluated with 3 consecutive acquisitions using a pyramidal aberrometer. Main outcome measures: The repeatability of different ocular higher-order aberrations and lower-order aberrations (HOAs and LOAs, respectively), and Zernike coefficients down to the fifth order, was evaluated. Repeatability was assessed by within-subject SDs (Sw), repeatability limits ( r ), and intraclass correlation coefficients (ICCs), among other parameters.

Results: 72 keratoconus patients (72 eyes) and 76 normal patients (76 eyes) were included. In normal and keratoconus eyes, the ICC of total LOAs and HOAs, as well as each of the Zernike coefficients, was >0.9. The Sw for keratoconus eyes with mean maximal keratometry (Kmax) <50 diopters (D) was 0.1345 for total LOAs, 0.0619 for total HOAs, 0.0292 for horizontal coma, 0.0561 for vertical coma, and 0.0221 for spherical aberration as compared with 0.2696, 0.1486, 0.0972, 0.1497, and 0.0757 for keratoconus eyes with Kmax ≥50 D. Similar trend of better repeatability for grade 1 keratoconus and HOAs <2 D as compared with grades 2 and 3 keratoconus and eyes with HOAs >2 D were also noted.

Conclusions: Ocular aberrometer measurements generated by high definition pyramidal aberrometers have high repeatability in both normal and mild keratoconus eyes and moderate repeatability, yet still clinically acceptable, in advanced keratoconus. This is of particular importance in ocular wavefront-guided treatments.

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来源期刊
CiteScore
5.60
自引率
14.30%
发文量
259
审稿时长
8.5 weeks
期刊介绍: The Journal of Cataract & Refractive Surgery (JCRS), a preeminent peer-reviewed monthly ophthalmology publication, is the official journal of the American Society of Cataract and Refractive Surgery (ASCRS) and the European Society of Cataract and Refractive Surgeons (ESCRS). JCRS publishes high quality articles on all aspects of anterior segment surgery. In addition to original clinical studies, the journal features a consultation section, practical techniques, important cases, and reviews as well as basic science articles.
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