机器人肾移植。

IF 12.1 1区 医学 Q1 UROLOGY & NEPHROLOGY Nature Reviews Urology Pub Date : 2024-03-13 DOI:10.1038/s41585-024-00865-z
Giuseppe Basile, Alessio Pecoraro, Andrea Gallioli, Angelo Territo, Camille Berquin, Jorge Robalino, Alejandra Bravo, Jorge Huguet, Óscar Rodriguez-Faba, Pavel Gavrilov, Carmen Facundo, Lluis Guirado, Josep Maria Gaya, Joan Palou, Alberto Breda
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摘要

与透析相比,肾移植能提高患者的存活率和生活质量,因此是终末期肾病患者的最佳治疗选择。在过去的 50 年中,肾移植的手术方法一直处于停滞状态,开放式方法是唯一的选择。在这种情况下,有证据表明,在多个外科领域引入机器人技术后,与手术相关的发病率有所降低,这促使外科医生考虑将机器人辅助肾移植(RAKT)作为治疗这些免疫功能低下的脆弱患者的另一种方法。2014年,在Vattikuti泌尿外科研究所和Medanta医院(Vattikuti泌尿外科研究所-Medanta)的开创性合作下,RAKT技术实现了标准化,此后,全球多家中心实施了RAKT计划,在该手术的安全性和可行性方面取得了令人感兴趣的成果。然而,RAKT仍被认为是一种主要在活体供体环境下提供的替代手术,因为它可能存在各种缺点,例如回温时间长、学习曲线要求高,以及在具有挑战性的情况下(如肥胖患者、严重的髂血管动脉粥样硬化、死亡供体环境或儿科受体)实施该手术存在困难。尽管如此,通过采用新技术完善机器人平台,以及在欧洲泌尿外科协会机器人泌尿外科分会的保护下开展多中心合作所取得的令人鼓舞的成果,目前正在扩大RAKT的范围,使该手术成为开放式方法的真正替代方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Robotic kidney transplantation
Kidney transplantation is the best treatment option for patients with end-stage renal disease owing to improved survival and quality of life compared with dialysis. The surgical approach to kidney transplantation has been somewhat stagnant in the past 50 years, with the open approach being the only available option. In this scenario, evidence of reduced surgery-related morbidity after the introduction of robotics into several surgical fields has induced surgeons to consider robot-assisted kidney transplantation (RAKT) as an alternative approach to these fragile and immunocompromised patients. Since 2014, when the RAKT technique was standardized thanks to the pioneering collaboration between the Vattikuti Urology Institute and the Medanta hospital (Vattikuti Urology Institute-Medanta), several centres worldwide implemented RAKT programmes, providing interesting results regarding the safety and feasibility of this procedure. However, RAKT is still considered an alternative procedure to be offered mainly in the living donor setting, owing to various possible drawbacks such as prolonged rewarming time, demanding learning curve, and difficulties in carrying out this procedure in challenging scenarios (such as patients with obesity, severe atherosclerosis of the iliac vessels, deceased donor setting, or paediatric recipients). Nevertheless, the refinement of robotic platforms through the implementation of novel technologies as well as the encouraging results from multicentre collaborations under the umbrella of the European Association of Urology Robotic Urology Section are currently expanding the boundaries of RAKT, making this surgical procedure a real alternative to the open approach. Robot-assisted kidney transplantation is gaining momentum in kidney transplantation programmes as an alternative approach to patients with end-stage renal disease. In this Review, the authors provide an overview of available evidence on robot-assisted kidney transplantation, particularly in clinically challenging scenarios.
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来源期刊
Nature Reviews Urology
Nature Reviews Urology 医学-泌尿学与肾脏学
CiteScore
12.50
自引率
2.60%
发文量
123
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.
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