多胎妊娠先天畸形:文献综述。

IF 4.3 4区 医学 Q1 OBSTETRICS & GYNECOLOGY Obstetrical & Gynecological Survey Pub Date : 2024-03-01 DOI:10.1097/OGX.0000000000001251
Jae Eun Shin, Hyun Sun Ko, Jin Young Bae, Won Joon Seong, Tae Gyu Ahn, You Jung Han, Geum Joon Cho, In Yang Park
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引用次数: 0

摘要

重要性:多胎妊娠在许多国家都比较常见,与各种妊娠并发症有关,包括早产、低出生体重和先天性畸形。特别是有报道称,与单胎妊娠相比,多胎妊娠中先天畸形与其他妊娠并发症重叠时,预后较差:本研究回顾了多胎妊娠与单胎妊娠相比发生先天性畸形的特点:本研究回顾了多胎妊娠与单胎妊娠相比发生先天性异常的特点。本文献综述全面覆盖了多胎妊娠先天性异常的情况:大多数研究表明,与单胎妊娠相比,多胎妊娠发生先天性异常的风险更高。此外,还观察到单卵双胎与双卵双胎的先天畸形率和一致率更高。辅助生殖疗法对多胎妊娠先天性异常风险的影响似乎小于单胎妊娠:结论:多胎妊娠与先天性畸形风险的增加密切相关:本综述为产科医生提供了必要的知识,以便为多胎妊娠患者提供适当的产前护理和产前异常筛查。
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Congenital Anomalies in Multiple Pregnancy: A Literature Review.

Importance: Multiple pregnancy is relatively common in many countries and is associated with various pregnancy complications, including preterm birth, low birth weight, and congenital anomalies. In particular, a poorer prognosis has been reported when congenital anomalies overlap with other pregnancy complications in multiple pregnancy compared with singleton pregnancy.

Objective: This study reviews the characteristics of congenital anomalies that occur in multiple gestations as compared with singleton pregnancies.

Evidence acquisition: An extensive manual search of major electronic databases was conducted in June 2023. This literature review provides a comprehensive coverage of the congenital anomalies in multiple pregnancy.

Results: Most studies have shown that multiple gestations are associated with an increased risk of congenital anomalies compared with singleton pregnancies. In addition, higher rates of congenital anomalies and concordance have been observed in monozygotic versus dizygotic twins. The effect of assisted reproductive therapies on the risk of congenital anomalies appears to be smaller in multiple gestations than in singleton pregnancies.

Conclusions: Multiple pregnancy is significantly associated with an increased risk of congenital anomalies.

Relevance: This review provides obstetrical providers with the requisite knowledge to offer appropriate antenatal care and prenatal anomaly screening to patients with multiple pregnancies.

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来源期刊
CiteScore
2.70
自引率
3.20%
发文量
245
审稿时长
>12 weeks
期刊介绍: ​Each monthly issue of Obstetrical & Gynecological Survey presents summaries of the most timely and clinically relevant research being published worldwide. These concise, easy-to-read summaries provide expert insight into how to apply the latest research to patient care. The accompanying editorial commentary puts the studies into perspective and supplies authoritative guidance. The result is a valuable, time-saving resource for busy clinicians.
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