伊巴丹大学学院医院头颈部皮肤癌患者的表现、临床效果和生活质量。

Afieharo I Michael, Ebere O Ugwu, Olayinka A Olawoye, Samuel A Ademola, Odunayo M Oluwatosin
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引用次数: 0

摘要

导言:头颈部皮肤癌患者会因疾病和/或治疗而在功能、社会心理和经济方面受到不利影响。本研究旨在评估头颈部皮肤癌患者的发病模式、临床结果和生活质量:对2017年1月至2021年12月期间到伊巴丹大学学院医院整形、修复和美容外科就诊的头颈部皮肤癌患者进行回顾性横断面研究。从临床记录中获得的数据包括社会人口学特征、临床和手术细节以及临床结果。生活质量采用 EORTC QLQ-C30 问卷进行评估。数据采用描述性统计进行总结:19名患者的中位年龄为38岁(18至85岁不等),男女比例为1:1.4。八名患者(42.1%)为白化病患者。鳞状细胞癌是主要的组织学类型(63.2%),而头皮是最常见的发病部位(42.1%)。只有一名患者(5.3%)出现转移性疾病。在接受治疗的患者中,以手术作为唯一治疗方式的患者比例较高,共有 8 人(61.5%)。平均随访时间为 33 个月,结果显示复发率为 10.5%(两名患者),死亡率为 15.8%(三名患者)。生活质量评估显示,白化病对患者的经济造成了不利影响:尽管白化病是皮肤癌的公认风险因素,但黑皮肤患者也可能患头颈部皮肤癌。
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Presentation, Clinical Outcome, and Quality of Life of Patients Treated for Head and Neck Skin Cancer at the University College Hospital, Ibadan.

Introduction: Patients with head and neck skin cancer experience adverse functional, psychosocial, and financial impacts as a result of the disease and/or its treatment. This study aimed at evaluating the pattern of presentation, clinical outcomes, and quality of life of patients with head and neck skin cancer.

Materials and methods: A retrospective cross-sectional study of patients with head and neck skin cancer presenting to the Department of Plastic, Reconstructive & Aesthetic Surgery of the University College Hospital, Ibadan, from January 2017 to December 2021. Data obtained from the clinical records included sociodemographic characteristics, clinical and surgical details, as well as clinical outcomes. Quality of life was assessed using EORTC QLQ-C30 questionnaires. Data were summarized using descriptive statistics.

Results: Nineteen patients were reviewed with a median age of 38 years (ranging from 18 to 85 years) and a male-to-female ratio of 1:1.4. Eight (42.1%) of the patients were albinos. Squamous cell carcinoma was the predominant histologic type (63.2%), while the scalp was the commonest location (42.1%). Only one patient (5.3%) presented with metastatic disease. A greater percentage of treated patients, eight (61.5%), had surgery as the only treatment modality. After a mean follow-up period of 33 months, a recurrence rate of 10.5% (two patients) and a mortality rate of 15.8% (three patients) were recorded. Quality of life assessment revealed an adverse financial impact of the disease on our patients.

Conclusion: Although albinism is a recognized risk factor for skin cancers, head and neck skin cancers can occur in the dark-skinned.

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