糖尿病胃轻瘫:一种难以获得长期治疗效果的疾病。

Endokrynologia Polska Pub Date : 2024-01-01 Epub Date: 2024-03-18 DOI:10.5603/ep.97086
Jun Zhou, Sha Li Ran, Ying Chang Zhao
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引用次数: 0

摘要

糖尿病胃轻瘫(DGP)是糖尿病患者常见的并发症,其病理生理学尚不完全清楚。其发病与多种原因有关,包括高血糖、迷走神经功能障碍、卡雅尔间质细胞网络(ICC)异常、肌间神经丛缺乏神经一氧化氮合酶(nNOS)表达以及胃肠道激素变化。葡萄糖管理、饮食控制、促胃动力药、止吐药、根除幽门螺旋杆菌、胃电刺激和手术是目前的主要治疗方法。然而,这些方法可能会产生不良后果。通过研究近期的研究和文献综述,我们在本文中概述了糖尿病胃瘫的研究现状。
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Diabetic gastroparesis: a disease for which long-term therapeutic benefits are difficult to obtain.

The pathophysiology of diabetic gastroparesis (DGP), a common complication in diabetic patients, is not fully known. Its development has been linked to several causes, including hyperglycaemia, vagal nerve dysfunction, aberrant Cajal's interstitial cell network (ICC), lack of nerve nitric oxide synthase (nNOS) expression in the intermuscular plexus, and hormonal alterations in the gastrointestinal tract. Glucose management, diet control, gastric stimulants, anti-emetic medications, Helicobacter pylori eradication, stomach electrical stimulation, and surgery are the main current treatments. These methods, however, could have unfavourable consequences. By examining recent studies and literature reviews, we outline the state of the study on diabetic gastroparesis in this paper.

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