急性中风护理中的机器学习:评估肠内营养需求的新型模型

Kazuhiro Okamoto, Keisuke Irie, Kengo Hoyano, Isao Matsushita
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摘要

目的:对于口服摄入有困难的急性脑卒中患者,通常建议尽早进行肠内营养。本研究旨在开发一种预测模型,用于评估急性脑血管疾病老年患者对肠内营养的需求。该模型采用机器学习算法,使用与吞咽能力相关的观察参数:本研究纳入了 90 名首次经历脑血管意外的患者。吞咽功能使用食物摄入量LEVEL量表进行评估。九个特定变量被用于创建一个确定肠内营养需求的模型。首先,通过相关分析选择变量。随后,数据被随机分为训练组和测试组。为了找出最有效的算法,我们采用了五种机器学习方法:逻辑回归、决策树、随机森林、支持向量机和 XG Boost:通过相关分析,我们确定了自变量功能独立性测量(Functional Independence Measure)、运动和认知评分以及语言清晰度。逻辑回归模型表现出很高的性能(准确率为 0.82;曲线下面积为 0.82):我们证明了一个采用机器学习并整合了功能独立性测量运动和认知评分以及语言智能的预测模型具有卓越的预测功效,并能确定肠内营养的必要性。即使不是吞咽困难方面的专家,也能对该模型进行快速评估。此外,它还适用于因意识障碍或认知障碍而无法遵守传统吞咽评估方案的患者,或吸入风险特别高的患者。
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Machine Learning in Acute Stroke Care: A Novel Model for Assessing the Need for Enteral Nutrition
Aim: Early enteral nutrition is often recommended for patients with acute stroke who have difficulty with oral intake. This study aimed to develop a predictive model to assess the need for enteral nutrition in older patients with acute cerebrovascular disorders. The model employs a machine learning algorithm using observational parameters related to swallowing ability. Methods: Ninety patients experiencing a cerebrovascular accident for the first time were included in this study. Swallowing function was assessed using the Food Intake LEVEL Scale. Nine specific variables were used to create a model for determining the need for enteral nutrition. Initially, variable selection was conducted through correlation analysis. Subsequently, the data were randomly divided into training and test groups. Five machine learning methods were applied to identify the most effective algorithm: logistic regression, decision tree, random forest, support vector machine, and XG Boost. Results: Through correlation analysis, we identified the independent variables Functional Independence Measure, motor and cognitive scores and speech intelligibility. The logistic regression model demonstrated high performance (accuracy, 0.82; area under the curve, 0.82). Conclusion: We demonstrated that a predictive model, employing machine learning and integrating Functional Independence Measure motor and cognitive scores and speech intelligibility, exhibits superior predictive efficacy and ascertains the necessity for enteral nutrition. This model can be expediently appraised even by individuals not specialized in dysphagia. Additionally, it is applicable to patients who are incapable of adhering to conventional swallowing assessment protocols owing to compromised consciousness or cognitive impairments, or those with an exceptionally elevated risk of aspiration.
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