更正 "阴离子肺表面活性物质磷脂的抗炎和抗病毒特性"。

IF 7.5 2区 医学 Q1 IMMUNOLOGY Immunological Reviews Pub Date : 2024-03-21 DOI:10.1111/imr.13320
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引用次数: 0

摘要

Numata M, Kandasamy P, Voelker DR.阴离子肺表面活性磷脂的抗炎和抗病毒特性。Immunol Rev. 2023; 317: 166-186.doi:10.1111/imr.13207在文章中,摘要部分不慎添加了第二段,应予以删除。摘要如下:次要阴离子肺表面活性磷脂 POPG 和 PI 作为多种 TLR 的拮抗剂表现出抗炎作用。作为抗病毒药物,这些磷脂对多种呼吸道 RNA 病毒(如 RSV、IAV 和 SARS-CoV-2)也有很强的疗效。PI 对无包膜病毒(人鼻病毒 A)也有很强的抑制作用。这些脂质还具有很强的潜力,可用作细胞因子风暴(包括严重的 COVID-19)诱发的急性肺损伤的抗炎化合物。我们测定了 POPG 对五种 RSV 临床分离株(以 GenBank 编号命名)和 RSV 重组株(rA2-A2F、rA2-19F 和 rA2 Long F)的抗病毒效力,并与 RSV-A2 进行了比较12。每种毒株的滴度以 PFU/mL 表示,POPG 和 POPC(200 μg/mL)对每种毒株的效力以斑块检测的病毒滴度表示。数据以两个独立实验的平均值±标度表示。摘要应为:小阴离子肺表面活性磷脂 POPG 和 PI 作为多种 TLR 的拮抗剂,具有抗炎作用。作为抗病毒药物,这些磷脂对多种呼吸道 RNA 病毒(如 RSV、IAV 和 SARS-CoV-2)也有很强的疗效。PI 对无包膜病毒(人鼻病毒 A)也有很强的抑制作用。这些脂质还具有很强的潜力,可用作细胞因子风暴(包括严重的 COVID-19)诱发的急性肺损伤的抗炎化合物。
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Correction to “The anti-inflammatory and antiviral properties of anionic pulmonary surfactant phospholipids”

Numata M, Kandasamy P, Voelker DR. The anti-inflammatory and antiviral properties of anionic pulmonary surfactant phospholipids. Immunol Rev. 2023; 317: 166–186. doi:10.1111/imr.13207

In the article, the second paragraph was inadvertently added to Summary section and should have been removed.

The Summary reads:

The minor anionic pulmonary surfactant phospholipids, POPG and PI, exhibit anti-inflammatory effects as antagonists for multiple TLRs. These lipids also have strong efficacies as antivirals against multiple respiratory RNA-enveloped viruses such as RSV, IAVs, and SARS-CoV-2. PI also has a potent effect against non-enveloped virus (human rhinovirus A). These lipids also have very strong potential to be applied as anti-inflammatory compounds for acute lung injury, induced by cytokine storms, including severe COVID-19.

We determined the antiviral efficacy of POPG against five clinical isolates of RSV (designated by GenBank accession numbers) and recombinant strains of RSV (rA2-A2F, rA2-19F, and rA2 Long F) in comparison with RSV-A2.12 The titer of each strain is shown as PFU/mL, and the efficacies of POPG and POPC (200 μg/mL) on each strain are stated as the viral titers by plaque assays. Data are shown as means ± SD from two independent experiments.

The Summary should read:

The minor anionic pulmonary surfactant phospholipids, POPG and PI, exhibit anti-inflammatory effects as antagonists for multiple TLRs. These lipids also have strong efficacies as antivirals against multiple respiratory RNA-enveloped viruses such as RSV, IAVs, and SARS-CoV-2. PI also has a potent effect against non-enveloped virus (human rhinovirus A). These lipids also have very strong potential to be applied as anti-inflammatory compounds for acute lung injury, induced by cytokine storms, including severe COVID-19.

We apologize for this error.

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来源期刊
Immunological Reviews
Immunological Reviews 医学-免疫学
CiteScore
16.20
自引率
1.10%
发文量
118
审稿时长
4-8 weeks
期刊介绍: Immunological Reviews is a specialized journal that focuses on various aspects of immunological research. It encompasses a wide range of topics, such as clinical immunology, experimental immunology, and investigations related to allergy and the immune system. The journal follows a unique approach where each volume is dedicated solely to a specific area of immunological research. However, collectively, these volumes aim to offer an extensive and up-to-date overview of the latest advancements in basic immunology and their practical implications in clinical settings.
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