体育锻炼是缓解期肠道疾病的有效辅助疗法(综述)

S. Kostyukevich, I. Bakulin
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摘要

炎症性肠病(IBD)包括克罗恩病和溃疡性结肠炎。IBD 是一种慢性疾病,有缓解和复发的轨迹。IBD 的药物治疗不够有效。因此需要对 IBD 进行辅助治疗。本综述旨在介绍运动的作用及其对 IBD 的影响。在这方面,人们正在寻找更多的工具,以提高达到和维持缓解的频率。最近有证据表明,运动能诱导一连串的抗炎细胞因子,特别是由肌肉白细胞介素 6 的指数级增加所引发,在缓解期定期运动可降低循环炎症标志物的基础水平,并有可能减少 IBD 的慢性炎症。医生建议患者在缓解期进行体育锻炼,这可以作为抗复发治疗的一个额外组成部分。
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Physical exercises as an effective adjuvant therapy of IBD in remission (review)
Inflammatory bowel diseases (IBD) include Crohn’s disease and ulcerative colitis. IBDs are chronic diseases with a trajectory of remission and relapse. Drug therapy for IBD is not effective enough. There is a need for adjuvant therapy for IBD. The purpose of this review was to present the role of exercise and its impact on IBD. In this regard, a search is underway for additional tools to increase the frequency of achieving and maintaining remission. There is recent evidence that exercise induces a cascade of anti-inflammatory cytokines, specifically triggered by an exponential increase in muscle interleukin 6, and with regular exercise during remission may reduce basal levels of circulating inflammatory markers and potentially reduce chronic inflammation in IBD. Doctor’s recommendations for physical activity during remission can be effective as an additional component of anti-relapse treatment.
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