评估成人 2 片和 16 片 CT 扫描过程中的患者剂量

Ebbi Donald Robinson, Chinyere Philomena Ononugbo, Oliver Gbarato
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Radiation dose was measured with a coded themoluminiscent dosimeter (TLD) chip, placed on the glabella and held in position with a transparent adhesive tape before the exposures and removed immediately after the investigation, labeled and sent to the Radiation Dosimetric Laboratory of the Regional Centre for Energy Research and Training (CERT), Zaria for reading. The effective dose was obtained from the absorbed dose by multiplying the absorbed dose with tissue weighting factor of 0.01 for the brain. The cancer and hereditary effects per investigation were obtained by using the cancer risk coefficients (FCR = 5.5X10−2 Sv−1) and hereditary risk coefficients (FGE = 0.2X10−2 Sv−1) obtained from ICRP 103 publication. All variables collated were tabulated into a data sheet and analyzed using Statistical Package for Social Sciences (SPSS) windows version 22.30 statistical software (SPSS Inc, Chicago, Illionois, USA). The results were presented on tables, charts and graphs. 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引用次数: 0

摘要

目的:计算机断层扫描(CT)是一项创新,为现代医学做出了巨大贡献。CT 使用 X 射线形式的电离辐射,这已成为一个令人担忧的问题。本研究旨在评估成人 2 片和 16 片 CT 扫描过程中的患者剂量。研究设计: 本研究为实证研究。研究地点和时间:在哈科特港的两家放射科机构分别对 50 名转诊患者进行脑 CT 扫描,分别进行 2 片和 16 片 CT 扫描,为期 6 个月。检查方法:检查按照脑 CT 标准协议进行。辐射剂量是用编码的发光剂量计(TLD)芯片测量的,该芯片在照射前放置在髌骨上并用透明胶带固定,检查结束后立即取下,贴上标签并送往扎里亚地区能源研究与培训中心(CERT)的辐射剂量测定实验室进行读数。将吸收剂量乘以 0.01 的脑组织加权系数,即可得出有效剂量。每次调查的癌症和遗传影响是通过使用从国际癌症研究委员会第 103 号出版物中获得的癌症风险系数(FCR = 5.5X10-2 Sv-1)和遗传风险系数(FGE = 0.2X10-2 Sv-1)得出的。整理出的所有变量均以表格形式记录在数据表中,并使用社会科学统计软件包(SPSS)视窗版 22.30 统计软件(SPSS Inc, Chicago, Illionois, USA)进行分析。分析结果以表格、图表和图形的形式呈现。描述性统计工具用于确定中心趋势,而皮尔逊相关和线性回归分析模型则用于评估变量之间的相关性。结果在 2 片和 16 片 CT 过程中,平均吸收剂量(±SD)分别为 51.37(±8.07)mSv 和 89.97±13.25mSv。在 2 片和 16 片 CT 程序中,终生可归属风险分别约为每 105 次 CT 程序中 3 次和 5 次,而在 2 片和 16 片 CT 程序中,遗传风险分别为每 106 次 CT 程序中 1 次和 2 次。体重指数与癌症风险之间存在微弱的相关性,皮尔逊相关系数(r)为 0.130,但在 2 片 CT 扫描过程中,癌症风险与年龄之间没有关联。结论吸收剂量会随着 CT 片数的增加而增加,同样,癌症和遗传风险也会随着 CT 片数的增加而增加。因此,尽管辐射量很低,但仍有可能导致恶性风险。
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Evaluation of Patients Doses During 2 and 16 Slice CT Scan Procedure in Adults
Aim: Computed tomography (CT) is an innovation that has contributed immensely to modern medicine. CT uses ionising radiation in the form of x-rays which has become a source of concern. The study is to evaluate patients’ doses during 2 and 16 slices CT scan procedure in adults. Study Design:  The study was an empirical study. Place and Duration of Study: It was carried out with 50 patients referred for brain CT in two separate radiology facilities having 2 and 16 slices CT scans in Port Harcourt over 6months duration. Methodology: The examination was done in accordance with standard protocols for brain CT. Radiation dose was measured with a coded themoluminiscent dosimeter (TLD) chip, placed on the glabella and held in position with a transparent adhesive tape before the exposures and removed immediately after the investigation, labeled and sent to the Radiation Dosimetric Laboratory of the Regional Centre for Energy Research and Training (CERT), Zaria for reading. The effective dose was obtained from the absorbed dose by multiplying the absorbed dose with tissue weighting factor of 0.01 for the brain. The cancer and hereditary effects per investigation were obtained by using the cancer risk coefficients (FCR = 5.5X10−2 Sv−1) and hereditary risk coefficients (FGE = 0.2X10−2 Sv−1) obtained from ICRP 103 publication. All variables collated were tabulated into a data sheet and analyzed using Statistical Package for Social Sciences (SPSS) windows version 22.30 statistical software (SPSS Inc, Chicago, Illionois, USA). The results were presented on tables, charts and graphs. A descriptive statistical tool was used to - determine central tendencies while Pearson correlation and linear regression analysis model was used to evaluate correlation between variables. Results: The mean absorbed dose (±SD) was 51.37(±8.07)mSv and 89.97±13.25mSv during 2 and 16 slices CT procedures respectively. The Lifetime Attributable Risk is approximately 3 and 5 per 105 CT procedures during 2 and 16 slice CT procedures while the Hereditary Risks was 1 and 2 per 106 CT procedures for 2 and 16 slice CT procedures respectively. There was a weak correlation between BMI and cancer risk with a Pearson Correlation coefficient (r) of 0.130 but no association between cancer risk and age during 2 slice CT scanner. Conclusion: Absorbed dose increases with increase on the CT slices, likewise cancer and hereditary risk increases with increase in CT slices. Thus, notwithstanding how low a radiation exposure could be it can still necessitate malignant risk.
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