关节置换术中的脉冲灌洗:系统回顾和荟萃分析

M. Daher, Gaby Haykal, Marven Aoun, Marc Moussallem, A. Ghoul, Jean Tarchichi, A. Sebaaly
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引用次数: 0

摘要

背景 膝关节和髋关节骨关节炎影响着全球数百万人,随着人口老龄化,预计其发病率还会进一步上升。关节置换术是治疗这些关节的首选手术方法。异位骨化和放射线形成分别是髋关节和膝关节置换术中经常遇到的两个问题。一些研究表明,使用脉冲灌洗可防止其形成。目的 比较关节置换术中脉冲灌洗与标准灌洗的效果。方法 搜索 PubMed、Cochrane 和 Google Scholar(第 1-20 页),直至 2023 年 12 月。仅纳入了对比研究。评估的临床结果包括髋关节置换术中的异位骨化形成、放射线形成和膝关节置换术中的膝关节功能评分。结果 四项研究符合纳入标准,被纳入本次荟萃分析。研究显示脉冲灌洗可减少放射线的形成(P = 0.001)。结论 脉冲灌洗可减少膝关节置换术中放射线的形成。其余结果无差异。此外,人们对这些放射线的临床意义知之甚少。需要更好的随机对照研究和成本效益研究来巩固这些发现。
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Pulsed lavage in joint arthroplasty: A systematic review and meta-analysis
BACKGROUND Knee and hip osteoarthritis affects millions of people around the world and is expected to rise even more in frequency as the population ages. Joint arthroplasty is the surgical management of choice in these articulations. Heterotopic ossification and radiolucent lines formation are two frequent problems faced in hip and knee replacements respectively. Some studies show that the usage of pulsed lavage may prevent their formation. AIM To compare pulsed lavage to standard lavage in joint arthroplasty. METHODS PubMed, Cochrane, and Google Scholar (page 1-20) were searched till December 2023. Only comparative studies were included. The clinical outcomes evaluated were the heterotopic ossification formation in hip replacements, radiolucent lines formation, and functional knee scores in knee replacements. RESULTS Four studies met the inclusion criteria and were included in this meta-analysis. Pulsed lavage was shown to reduce the formation of radiolucent lines (P = 0.001). However, no difference was seen in the remaining outcomes CONCLUSION Pulsed lavage reduced the formation of radiolucent lines in knee replacements. No difference was seen in the remaining outcomes. Furthermore, the clinical significance of these radiolucent lines is poorly understood. Better conducted randomized controlled studies and cost-effectivity studies are needed to reinforce these findings.
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