患有先天性精神疾病的重症儿童的治疗效果

IF 1.9 4区 医学 Q2 PEDIATRICS Pediatric Investigation Pub Date : 2024-03-18 DOI:10.1002/ped4.12422
C. Krawiec, Morgan Cash, G. Ceneviva, Zizhong Tian, Shouhao Zhou, Neal J. Thomas
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引用次数: 0

摘要

这项回顾性观察队列研究利用 TriNetX 电子健康记录数据库对 12-18 岁的重症患者进行了分析。从 102 027 名重症儿童的数据集中,我们分析了 1999 名受试者(284 人 [14.2%]患有既往精神疾病,1715 人 [85.8%] 没有既往精神疾病)。多变量分析表明,即使在控制了是否存在复杂的慢性疾病后,一年内的死亡仍与是否存在既往精神健康状况有关(几率比 8.97 [3.48-23.15],P < 0.001)。然而,置信区间较宽,因此研究结果并不确定。未来的研究可能需要更大的样本量,以评估需要接受重症监护服务的原有精神健康状况儿童的真正长期影响。
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Outcomes of critically ill children with pre‐existing mental health conditions
Critically ill children with pre‐existing mental health conditions may have an increased risk of poor health outcomes.We aimed to evaluate if pre‐existing mental health conditions in critically ill pediatric patients would be associated with worse clinical outcomes, compared to children with no documented mental health conditions.This retrospective observational cohort study utilized the TriNetX electronic health record database of critically ill subjects aged 12–18 years. Data were analyzed for demographics, pre‐existing conditions, diagnostic, medication, procedural codes, and mortality.From a dataset of 102 027 critically ill children, we analyzed 1999 subjects (284 [14.2%] with a pre‐existing mental health condition and 1715 [85.8%] with no pre‐existing mental health condition). Multivariable analysis demonstrated that death within one year was associated with the presence of pre‐existing mental health conditions (odds ratio 8.97 [3.48–23.15], P < 0.001), even after controlling for the presence of a complex chronic condition.The present study demonstrates that the presence of pre‐existing mental health conditions was associated with higher odds of death within 1 year after receiving critical care. However, the confidence interval was wide and hence, the findings are inconclusive. Future studies with a larger sample size may be necessary to evaluate the true long‐term impact of children with pre‐existing mental health conditions who require critical care services.
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来源期刊
Pediatric Investigation
Pediatric Investigation Medicine-Pediatrics, Perinatology and Child Health
CiteScore
3.30
自引率
0.00%
发文量
176
审稿时长
12 weeks
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