南非医护人员感染 SARS-CoV-2 后的急性后遗症

Sthembile Mbotwe-Sibanda, G. Kwatra, S. Madhi, Marta C. Nunes
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摘要

医护人员是主要的医疗服务提供者,因此确保他们得到保护并从 Covid-19 中康复是非常重要的。我们对曾经感染过 SARS-CoV-2 的医护人员进行了 SARS-CoV-2 感染急性后遗症(PASC)调查。根据症状持续的天数,共有 68 名高危工人被归类为 PASC。这 68 名有严重急性呼吸系统综合症的高危工人按其症状持续的平均天数分为两组,分别为(8 天)122 天和(60 天)641 天。患有急性呼吸系统综合症的华工报告的常见症状频率为持续头痛(45)、轻微咳嗽(41)、疲劳(37)、肌痛(25)和呼吸急促(14)。当使用医学研究委员会(MRC)的呼吸困难量表来检查 104 名患有帕金森病的高危产妇中的 68 人的呼吸困难程度与活动的关系时,我们发现 4 人(5.9%)报告在剧烈运动后呼吸困难,19 人(27.9%)在快步行走或步行上小山时发现呼吸急促,2 人(3.0%)报告比步行慢。2人(3.0%)报告在平地上行走时比大多数人慢,或按自己的步速行走 15 分钟后停止,1 人(1.5%)报告在行走 91 米后或在平地上行走几分钟后停止呼吸,1 人(1.5%)报告气喘得不敢出门,或在穿衣/脱衣时气喘。我们的研究结果凸显了对长期持续存在症状的高危工人的关注,这些症状可能会对他们的健康产生负面影响,这也是一个新出现的公共卫生优先事项。有长期 Covid-19 症状(尤其是呼吸困难)的高危职业人群需要更好的诊断测试和治疗方法。
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Post-acute sequelae of SARS-CoV-2 infection in health care workers from South Africa
Health care workers (HCWs) are primary health providers therefore ensuring their protection and recovery from Covid-19 is of high interest. We investigated post-acute sequelae of SARS-CoV-2 infection (PASC) in HCWs who had previously been infected with SARS-CoV-2. Overall, 68 HCWs were classified as PASC according to duration in days of persisting symptoms. The 68 HCWs with PASC were split into two groups according to their mean duration of symptoms which were (8 PASC) 122 and (60 PASC) 641 days. The frequencies of common symptoms reported by HWCs with PASC were continuous headaches (45), mild cough (41), fatigue (37), myalgia (25) and shortness of breath (14). When Using the Medical Research Council (MRC) Dyspnoea Scale to examine the degree of breathlessness in relations to activity in the 68 out of the 104 HCWs with PASC we found that 4 (5.9%) reported having difficulty breathing after strenuous exercise, 19 (27.9%) were identified with shortness of breath when walking fast or when walking up a slight hill, 2 (3.0%) reported walking slower than most people on level or stopping after 15 minutes walking at own pace, 1 (1.5%) reported stopping to breath after walking 91 meters, or after a few minutes on level ground and 1 (1.5%) reported being too breathless to leave the house, or breathless when dressing/undressing. Our results highlight concern for HCWs with long-term persisting symptoms which may negatively impact their health this represents an emerging public health priority. HCWs with prolonged Covid-19 symptoms especially breathing difficulties need better diagnostic tests and treatments.
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