幽门螺杆菌与社会人口学特征分布

Amenah Jamal Shaiban, S. H. Nayyef
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摘要

导言和目的:幽门螺杆菌是一种革兰氏阴性菌,影响着全球多达一半的人口,尤其是在较贫穷的国家。它是慢性胃炎、溃疡、胃淋巴瘤和胃癌的主要病因,儿童和青少年中的发病率更高。可通过粪-口、胃-口、口-口或性途径传播。感染是由幽门螺杆菌的尿素酶活性、对宿主胃上皮细胞的侵袭以及对宿主细胞受体的粘附引起的。早期治疗可加强对胃的保护。材料与方法:2022 年 11 月至 2023 年 7 月期间,埃尔比勒市米赫拉巴尼外科医院收集了 103 份患者样本,以确定幽门螺杆菌感染情况。血液样本和粪便样本用于检测抗体。结果:研究发现,患者组和对照组的性别比例相对平等,患者组中男性占 48.48%,对照组中男性占 48.64%。然而,年龄分布存在明显差异,G3 年龄组(小于 35 岁)幽门螺杆菌感染率最高(48.48%)。此外,62.12% 的患者是农村居民,而对照组中 97.29% 的患者是城市居民。最后,56.07%的患者已婚,这表明两者之间存在显著差异。结论研究发现,患者组和对照组的性别比例相同,但在年龄、农村居民和婚姻状况方面存在显著差异,其中 35 岁以下的 G3 幽门螺杆菌感染率最高。
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Helicobacter Pylori and Sociodemographic Characteristics Distribution
Introduction and Aim: Helicobacter pylori is a gram-negative bacterium that affects up to half of the world's population, particularly in poorer nations. It is the leading cause of chronic gastritis, ulcers, gastric lymphoma, and gastric cancer, with more frequent cases in children and adolescents. Transmission can occur through fecal-oral, gastro-oral, oral-oral, or sexual means. The infection is caused by H. pylori's urease activity, invasion of host gastric epithelial cells, and adherence to host cell receptors. Early treatment can enhance gastric protection. Materials and Methods: Between November 2022 and July 2023, 103 samples were collected from patients at Mihrabani Surgical Hospital in Erbil City to identify Helicobacter pylori infection. Blood samples and stool samples were used to test for antibodies. Results: The study found a relatively equal gender representation in the patient and control groups, with 48.48% of men in the patient group and 48.64% in the control group. However, there are significant differences in age distribution, with G3 of age (<35) having the highest prevalence of H.pylori (48.48%). Additionally, 62.12% of patients are rural residents, while 97.29% of the control group are urban residents. Finally, 56.07% of patients are married, indicating a significant difference. Conclusion: The study found equal gender representation in patient and control groups but significant age differences, rural residency, and marital status, with G3 under 35 having the highest H.pylori prevalence.
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