(017) 比较同时植入充气阴茎假体/人工尿道括约肌与充气阴茎假体/男性吊带的并发症发生率和连续性控制:最新比较试验研究

K. Khalaf Alla, M. Mahdi, J. Mehr, O. Westney, R. Wang
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Recent clinical trials have aimed to determine the comparative effectiveness between the male sling and the artificial urinary sphincter (AUS) in men with urodynamic stress urinary incontinence (SUI) after prostate surgery, focusing on non-inferiority.\n \n \n \n We aim to compare continence control and complications rates in patients who underwent bulbourethral slings or AUS during IPP surgery via perineal approach.\n \n \n \n A retrospective chart review was done in a large tertiary center. Post prostatectomy patients who underwent perineal dual implantation IPP and AUS or bulbourethral sling for ED and UI purposes, between 2014 and 2022 were included. Clinical data, patients’ demographics were retrieved. Post-operative outcomes with regards to IPP complication rates, revision rates for IPP/ AUS / Male sling, and continence control at 6 weeks, 6 months and 1 year were collected and included in the analysis. 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引用次数: 0

摘要

人工尿道括约肌(AUS)和球部尿道男用吊带常用于治疗男性前列腺切除术后尿失禁(UI)。一些外科医生习惯于在同一手术中结合充气阴茎假体 (IPP) 手术来治疗并发的勃起功能障碍 (ED)。最近的临床试验旨在确定男性吊带和人工尿道括约肌(AUS)对前列腺手术后尿动力压力性尿失禁(SUI)男性患者的比较效果,重点是非劣效性。 我们的目的是比较在经会阴入路的 IPP 手术中接受球部尿道吊带或 AUS 的患者的尿失禁控制率和并发症发生率。 我们在一家大型三级医疗中心进行了回顾性病历审查。研究纳入了2014年至2022年间接受会阴双重植入IPP和AUS或球部尿道吊带治疗ED和UI的前列腺切除术后患者。检索了临床数据和患者的人口统计学特征。收集并分析了术后结果,包括IPP并发症发生率、IPP/AUS/男用吊带翻修率以及6周、6个月和1年的尿失禁控制率。尿失禁控制率根据两组患者在后续随访中每天使用的尿垫数量进行评估。 共有 32 名患者符合纳入标准。16名患者接受了同步IPP和AUS插入术,另外16名患者接受了IPP和球部尿道吊带术。表 1 总结了患者的人口统计学特征、中位随访时间和并发症发生率。两组患者均通过会阴入路进行手术。两组患者的基线数据无明显差异。AUS 装置和球部尿道吊带的并发症发生率在统计学上无明显差异(分别为 12.5% vs 6.25% P=0.22)。感染率和翻修需求也没有明显的统计学差异。在术后尿失禁率方面,两组结果相当,无明显差异(P=0.81)。在6个月的随访中,AUS组有56%的患者无尿垫,19%的患者每天使用1块尿垫,19%的患者每天使用2块尿垫,6%的患者每天使用3块或3块以上尿垫,而吊带组有50%的患者无尿垫,25%的患者每天使用1块尿垫,19%的患者每天使用2块尿垫,6%的患者每天使用3块或3块以上尿垫。术后对患者进行了为期一年的随访。 IPP与AUS或吊带术联合插入,在尿失禁率和与设备相关的并发症方面具有可比性。每种尿失禁手术都应根据外科医生的经验和患者的具体适应症来选择。要巩固这些研究结果,还需要对更多的患者样本进行进一步的前瞻性研究,并延长随访时间,以指导患者做出决定,并在有适应症时优先选择尿失禁手术和 IPP。 不
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(017) Comparing Complication Rates and Continence Control in Concurrent Dual Implantation of Inflatable Penile Prosthesis/Artificial Urinary Sphincter vs. Inflatable Penile Prosthesis/Male Sling: An Updated Comparative Pilot Study
Artificial urinary sphincter (AUS) and bulbourethral male sling are used frequently in the management of post prostatectomy urinary incontinence (UI) in men. Some surgeons used to combine an inflatable Penile Prosthesis (IPP) procedure at the same setting to treat concurrent erectile dysfunction (ED). Recent clinical trials have aimed to determine the comparative effectiveness between the male sling and the artificial urinary sphincter (AUS) in men with urodynamic stress urinary incontinence (SUI) after prostate surgery, focusing on non-inferiority. We aim to compare continence control and complications rates in patients who underwent bulbourethral slings or AUS during IPP surgery via perineal approach. A retrospective chart review was done in a large tertiary center. Post prostatectomy patients who underwent perineal dual implantation IPP and AUS or bulbourethral sling for ED and UI purposes, between 2014 and 2022 were included. Clinical data, patients’ demographics were retrieved. Post-operative outcomes with regards to IPP complication rates, revision rates for IPP/ AUS / Male sling, and continence control at 6 weeks, 6 months and 1 year were collected and included in the analysis. Continence control rates were assessed by the number of pads used per day on subsequent follow up visits for both groups. A total of 32 patients met the inclusion criteria. 16 Patients underwent synchronous IPP and AUS insertion, whereas another 16 patients underwent IPP with bulbourethral sling procedure. Patient demographics, median follow up & complication rates are summarized below in Table 1. In both groups the procedure was done through a perineal approach. There was no significant difference in baseline data among groups. Complication rates between AUS devices and bulbourethral slings showed no statistically significant differences (12.5% vs 6.25% p= 0.22 respectively). Infection rates and need for revision also did not show any statistically significant differences. With regards to post-operative continence rates, both groups had comparable outcome with no significant differences (P = 0.81). Upon the 6 months follow up visit, the AUS group, 56% were pad free, 19% used 1 pad per day, 19% used 2 pads per day, and 6% used 3 pads or more per day, while in the sling group, 50% were pad free, 25% used 1 pad per day, 19% used 2 pads per day, and 6% used 3 pads or more per day. Patients were followed for a total of 1 year after the surgery. The combined insertion of IPP with either AUS or sling procedures has comparable outcomes with regards to continence rate and device- related complications. Each incontinence surgery should be chosen according to surgeon experience and specific patient indications. Further prospective studies on a larger sample of patients with longer follow up period are needed to solidify these findings and will guide patient's decision and preference for incontinence surgeries along with IPP once indicated. No.
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