摩洛哥监测系统中的先天性畸形:对患病率估算的贡献。

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-18 eCollection Date: 2024-01-01 DOI:10.1155/2024/9570798
Soukaina Kannane, Samia Boussaa, Jamila El Mendili, Oulaid Touloun
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引用次数: 0

摘要

背景:先天性畸形(CMs)是一组出生时就存在的结构或功能异常。这些畸形导致儿童死亡率、发病率和残疾率居高不下。CM畸形是一个重大的公共卫生问题,给包括摩洛哥在内的发达国家和发展中国家的医疗保健系统带来了沉重负担。本研究的目的是确定 CMs 在摩洛哥的发病率:在这项研究中,利用从 2017 年至 2021 年病例通报表中收集的国家监测系统数据,对摩洛哥的中医流行病学进行了回顾性评估:主要结果显示,摩洛哥的CMs患病率为3.91/1000活产(LBs),CMs的最低年度患病率出现在2017年(3.10/1000 LBs),而最高年度患病率则出现在2018年(4.55/1000 LBs)。绝大多数的CM为不明原因的CM(68.55%),神经管缺陷(NTD)占(21.13%),口面裂(OFC)占(10.32%)。此外,大多数中国儿童(61.73%)来自农村地区。根据地区划分,达赫拉-欧德埃达哈布(Dakhla-Oued Eddahab)地区的CM发病率最高,为8.81/1000 LB,而拉巴特-萨莱-凯尼特拉(Rabat-Sale-Kenitra)地区的发病率最低,为2.02/1000 LB:这项研究表明,由于报告的大多数中风病病因不明,全国中风病发病率很高,而且可能被低估。当务之急是使用 CM 登记册,详细报告所有 CM,并推广预防措施。
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Congenital Malformations in the Moroccan Surveillance System: Contribution to Prevalence Estimation.

Background: Congenital malformations (CMs) are a group of structural or functional anomalies present at birth. These anomalies result in a high rate of mortality, morbidity, and disability in children. CMs are a major public health problem and place a heavy burden on healthcare systems in both developed and developing countries including Morocco, which has had a CMs surveillance system in place since 2011. The aim of this study is to determine the prevalence of CMs in Morocco.

Methods: In this study, the epidemiology of CMs in Morocco was assessed retrospectively using the national surveillance system data gathered from case notification forms from 2017 to 2021.

Results: The main results showed that the prevalence of CMs in Morocco is 3.91/1000 live births (LBs), and the minimum annual prevalence of CMs was reached in 2017 (3.10/1000 LBs) while the maximum annual prevalence was recorded in 2018 (4.55/1000 LBs). The majority of CMs are unspecified CMs (68.55%), neural tube defects (NTDs) account for (21.13%), and orofacial clefts (OFCs) account for (10.32%). In addition, the majority of CMs (61.73%) were from rural areas. According to region, the Dakhla-Oued Eddahab region recorded the highest prevalence of CMs in Morocco, with 8.81/1000 LBs, while the lowest prevalence was recorded in the Rabat-Sale-Kenitra region, with 2.02/1000 LB.

Conclusions: This study reveals that the national prevalence of CMs is high and may be underestimated, as most of the CMS reported is unspecified. The use of a CM registry with detailed reporting of all CMs and the promotion of preventive measures are urgently recommended.

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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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