Rhiannon Stellmaker, Belinda Thompson, Helen Mackie, Louise Koelmeyer
{"title":"比较脂肪性水肿、淋巴水肿妇女和对照组参与者的体液和身体成分测量结果。","authors":"Rhiannon Stellmaker, Belinda Thompson, Helen Mackie, Louise Koelmeyer","doi":"10.1111/cob.12658","DOIUrl":null,"url":null,"abstract":"<p>Lipoedema is the disproportionate accumulation of adipose tissue in the lower body, often associated with hormonal changes in women. Lipoedema is commonly misdiagnosed as lymphoedema or obesity due to similarities in appearance. The aim of this study is to compare body composition and fluid measures of women with lipoedema, lymphoedema, and matched control participants, to determine differences that may help distinguish between each condition. One hundred and eleven participants aged over 18, who presented with the complaint of leg swelling and underwent indocyanine green lymphography were included in this study. Our analysis showed that the individuals with lymphoedema had a significantly higher overall total body water (<i>lymphoedema</i>: 9.6 ± 4.2 L, <i>lipoedem</i>a: 7.4 ± 2.3 L, <i>control</i>: 7.5 ± 1.8 L; <i>p</i> < .001) and extracellular fluid (<i>lymphoedema</i>: 4.6 ± 1.6, <i>lipoedema</i>: 3.4 ± 1.0 L, <i>control</i>: 3.5 ± 0.7 L; <i>p</i> < .001) in the legs when compared to individuals with lipoedema and matched control participants. Individuals with lipoedema had a significantly higher overall fat mass as a percentage of body weight when compared to individuals with lymphoedema (<i>lymphoedema</i>: 33.1% ± 9.5%, <i>lipoedema</i>: 39.4% ± 6.5%; <i>p</i> = .003). We are unable to distinguish between individuals with lipoedema and control participants, therefore further research needs to be conducted to help reduce misdiagnosis.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"14 4","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12658","citationCount":"0","resultStr":"{\"title\":\"Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants\",\"authors\":\"Rhiannon Stellmaker, Belinda Thompson, Helen Mackie, Louise Koelmeyer\",\"doi\":\"10.1111/cob.12658\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Lipoedema is the disproportionate accumulation of adipose tissue in the lower body, often associated with hormonal changes in women. Lipoedema is commonly misdiagnosed as lymphoedema or obesity due to similarities in appearance. The aim of this study is to compare body composition and fluid measures of women with lipoedema, lymphoedema, and matched control participants, to determine differences that may help distinguish between each condition. One hundred and eleven participants aged over 18, who presented with the complaint of leg swelling and underwent indocyanine green lymphography were included in this study. Our analysis showed that the individuals with lymphoedema had a significantly higher overall total body water (<i>lymphoedema</i>: 9.6 ± 4.2 L, <i>lipoedem</i>a: 7.4 ± 2.3 L, <i>control</i>: 7.5 ± 1.8 L; <i>p</i> < .001) and extracellular fluid (<i>lymphoedema</i>: 4.6 ± 1.6, <i>lipoedema</i>: 3.4 ± 1.0 L, <i>control</i>: 3.5 ± 0.7 L; <i>p</i> < .001) in the legs when compared to individuals with lipoedema and matched control participants. Individuals with lipoedema had a significantly higher overall fat mass as a percentage of body weight when compared to individuals with lymphoedema (<i>lymphoedema</i>: 33.1% ± 9.5%, <i>lipoedema</i>: 39.4% ± 6.5%; <i>p</i> = .003). We are unable to distinguish between individuals with lipoedema and control participants, therefore further research needs to be conducted to help reduce misdiagnosis.</p>\",\"PeriodicalId\":10399,\"journal\":{\"name\":\"Clinical Obesity\",\"volume\":\"14 4\",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.12658\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Obesity\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/cob.12658\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Obesity","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/cob.12658","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
Comparison of fluid and body composition measures in women with lipoedema, lymphoedema, and control participants
Lipoedema is the disproportionate accumulation of adipose tissue in the lower body, often associated with hormonal changes in women. Lipoedema is commonly misdiagnosed as lymphoedema or obesity due to similarities in appearance. The aim of this study is to compare body composition and fluid measures of women with lipoedema, lymphoedema, and matched control participants, to determine differences that may help distinguish between each condition. One hundred and eleven participants aged over 18, who presented with the complaint of leg swelling and underwent indocyanine green lymphography were included in this study. Our analysis showed that the individuals with lymphoedema had a significantly higher overall total body water (lymphoedema: 9.6 ± 4.2 L, lipoedema: 7.4 ± 2.3 L, control: 7.5 ± 1.8 L; p < .001) and extracellular fluid (lymphoedema: 4.6 ± 1.6, lipoedema: 3.4 ± 1.0 L, control: 3.5 ± 0.7 L; p < .001) in the legs when compared to individuals with lipoedema and matched control participants. Individuals with lipoedema had a significantly higher overall fat mass as a percentage of body weight when compared to individuals with lymphoedema (lymphoedema: 33.1% ± 9.5%, lipoedema: 39.4% ± 6.5%; p = .003). We are unable to distinguish between individuals with lipoedema and control participants, therefore further research needs to be conducted to help reduce misdiagnosis.
期刊介绍:
Clinical Obesity is an international peer-reviewed journal publishing high quality translational and clinical research papers and reviews focussing on obesity and its co-morbidities. Key areas of interest are: • Patient assessment, classification, diagnosis and prognosis • Drug treatments, clinical trials and supporting research • Bariatric surgery and follow-up issues • Surgical approaches to remove body fat • Pharmacological, dietary and behavioural approaches for weight loss • Clinical physiology • Clinically relevant epidemiology • Psychological aspects of obesity • Co-morbidities • Nursing and care of patients with obesity.