表现为腹内巨大肿物的小网膜胃肠道外间质瘤:病例报告和文献综述。

IF 0.9 Q4 ONCOLOGY Rare Tumors Pub Date : 2024-03-27 eCollection Date: 2024-01-01 DOI:10.1177/20363613241242572
John Adi Ashindoitiang, Victor Ikechukwu Canice Nwagbara, Theophilus Ipeh Ugbem, Nkami Joseph Enya, Ikechimka Ogbugbanduchi Aniebo, Joseph Christopher Ekong, Sidney Esotu Obinna, Maurice Efana Asuquo
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引用次数: 0

摘要

胃肠道外间质瘤(EGIST)很罕见,被视为起源于胃肠道外的胃肠道间质瘤(GIST)。它们起源于网膜、肠系膜和腹膜等其他腹腔内组织。肿瘤的起源细胞是卡贾尔间质细胞(ICC),这是一种控制胃肠蠕动的起搏细胞,其特征是表达跨膜酪氨酸激酶受体 KIT(CD117)。这里有一位 49 岁的女性患者,6 个月前出现腹痛、进行性腹部肿胀和上腹部肿块。经组织学和免疫组化确诊为小网膜EGIST,她接受了手术切除和伊马替尼辅助治疗。术后 14 个月的连续 CT 检查未发现复发或转移迹象。临床医生在鉴别诊断腹部肿块时应考虑 EGIST。
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Extra-gastrointestinal stromal tumour of the lesser omentum presenting as a massive intra-abdominal swelling: A case report and literature review.

Extra gastrointestinal stromal tumour(EGIST) is rare and is regarded as gastrointestinal stromal tumour(GIST) that originates outside of the gastrointestinal tract. They originate from other intraabdominal tissues such as the omentum, mesentery and peritoneum. The cell of origin is the interstitial cell of Cajal(ICC), a pacemaker cell that controls gastrointestinal peristalsis and the tumor is characterized by the expression of KIT(CD117) a transmembrane tyrosine kinase receptor. Here, a 49-year-old female who presented with a 6 month history of abdominal pain, progressive abdominal swelling and the presence of an upper abdominal mass. She had surgical resection and adjuvant imatinib for the intraabdominal mass diagnosed on histology and immunohistochemistry as EGIST of the lesser omentum. Serial CT 14 months after surgery revealed no evidence of recurrence or metastasis. Clinicians should consider EGIST in the differential diagnosis of abdominal masses.

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Rare Tumors
Rare Tumors ONCOLOGY-
CiteScore
1.50
自引率
0.00%
发文量
15
审稿时长
15 weeks
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