[细胞疗法和伤口修复]

Y Liu, X Y Liu
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引用次数: 0

摘要

细胞疗法包括活细胞疗法和基于细胞外囊泡和生物活性分子的细胞衍生疗法。作为近年来的研究热点,细胞疗法是解决临床难治性伤口修复问题的潜在策略。材料科学和细胞生物学的飞速发展为细胞疗法拉开了新的序幕,同时也为如何进一步优化细胞疗法并将其应用于伤口修复提出了新的命题。本文回顾了用于伤口治疗的细胞类型,总结了基于细胞治疗新技术的应用与探索,梳理了现有细胞疗法临床应用的难点,展望了细胞疗法用于伤口修复的未来发展趋势,以期推动创新细胞治疗体系的发展,进一步提高临床伤口治疗效果。
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[Cell therapy and wound repair].

Cell therapy includes living cell-based therapy and cell-derivative therapy that is based on extracellular vesicles and bioactive molecules. As a research hotspot in recent years, cell therapy is a potential strategy to solve the clinical problem of refractory wound repair. The rapid development of material science and cell biology has opened a new prelude to cell therapy, and at the same time, puts forward a new proposition on how to further optimize and apply cell therapy to wound repair. This article reviewed the cell types used for wound treatment, summarized the application and exploration of cell therapy-based new technologies, sorted out the difficulties in the clinical application of existing cell therapies, and looked into the future development trend of cell therapy for wound repair, in order to promote the development of innovative cell therapy system and further improve the clinical wound treatment effect.

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