女同性恋、男同性恋、双性恋和变性者群体中 Z 类药物的使用和苯并二氮杂卓的使用与滥用:心理压力的作用。

IF 4.2 3区 医学 Q1 SUBSTANCE ABUSE Journal of Addiction Medicine Pub Date : 2024-07-01 Epub Date: 2024-03-29 DOI:10.1097/ADM.0000000000001309
Vitor S Tardelli, Thiago M Fidalgo, Silvia S Martins
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引用次数: 0

摘要

背景:Z类药物(唑吡坦、佐匹克隆和扎来普隆等催眠药)和苯二氮卓类药物(BZD)是有滥用风险的镇静药物。本研究的目的是报告:(1) 按性身份类别和心理困扰分类,过去一年中使用任何 Z 类药物、使用任何 BZD 和滥用任何 BZD 的流行率;(2) 性身份与过去一年心理困扰之间这 3 个类别的关联;(3) 按过去一年心理困扰状况分类,这 3 个类别与性身份之间的关联:数据收集自全国药物使用和健康调查(2015-2019 年 [n = 210,392] ),这是一项针对美国人口的年度代表性全国家庭调查。我们按性身份和过去一年的心理困扰状况报告了任何 Z 类药物使用、任何 BZD 使用和任何 BZD 滥用的流行率。我们采用复杂的调查设计,以上述 3 个二分变量为因变量,按心理困扰进行分层和非分层,进行了逻辑回归:结果:在 LGB(女同性恋/男同性恋/双性恋)人群中,尤其是男同性恋和双性恋女性中,任何 Z 类药物和 BZD 的使用率以及任何 BZD 的滥用率都较高。心理困扰与使用 Z-药物和 BZD 以及滥用 BZD 呈正相关。女性使用 Z-drug(赔率 [OR],1.27;95% 置信区间 [CI],1.18-1.37)和 BZD(赔率,1.64;95% 置信区间 [CI],1.55-1.73)的风险较高,但滥用 BZD 的风险较低(赔率,0.82;95% 置信区间 [CI],0.76-0.88)。根据心理困扰进行分层时,过去一年没有心理困扰的男女同性恋者和异性恋者之间的差异更为明显,尤其是男同性恋者和双性恋女性:结论:心理困扰的存在缩小了男女同性恋、双性恋和变性者与异性恋之间在使用 Z 药物和 BZD 以及滥用 BZD 方面的差异。
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Z-Drug Use and Benzodiazepine Use and Misuse Among LGB Populations: The Role of Psychological Distress.

Background: Z-drugs (hypnotics such as zolpidem, zopiclone, and zaleplon) and benzodiazepines (BZDs) are sedative medications with misuse liability. The goals of this study are to report the (1) prevalence of past-year any Z-drug use, any BZD use, and any BZD misuse by sexual identity category and psychological distress; (2) associations among these 3 categories between sexual identity and past-year psychological distress; (3) associations among these 3 categories with sexual identity by past-year psychological distress status.

Methods: Data were collected from the National Survey on Drug Use and Health (years 2015-2019 [n = 210,392]), a yearly representative national household survey of the American population. We report prevalences of any Z-drug use, any BZD use, and any BZD misuse by sexual identity and past-year psychological distress status. We ran logistic regressions with complex survey design with the 3 dichotomous variables described above as the dependent variables, stratified and not-stratified by psychological distress.

Results: Prevalence of any Z-drug an BZD use and any BZD misuse were higher among LGB (lesbian/gay/bisexual) populations, especially gay men and bisexual women. Psychological distress was positively associated with any Z-drug and BZD use and any BZD misuse. Women were at higher risk of Z-drug (odds ratio [OR], 1.27; 95% confidence interval [CI], 1.18-1.37) and BZD use (OR, 1.64; 95% CI, 1.55-1.73), but lower risk of BZD misuse (OR, 0.82; 95% CI, 0.76-0.88). When stratifying by psychological distress, differences between LGB and heterosexuals were more pronounced among those without past-year psychological distress, especially gay men and bisexual women.

Conclusions: The presence of psychological distress attenuates the disparities between LGB and heterosexual individuals in Z-drug use and BZD use and misuse.

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来源期刊
Journal of Addiction Medicine
Journal of Addiction Medicine 医学-药物滥用
CiteScore
6.10
自引率
9.10%
发文量
260
审稿时长
>12 weeks
期刊介绍: The mission of Journal of Addiction Medicine, the official peer-reviewed journal of the American Society of Addiction Medicine, is to promote excellence in the practice of addiction medicine and in clinical research as well as to support Addiction Medicine as a mainstream medical sub-specialty. Under the guidance of an esteemed Editorial Board, peer-reviewed articles published in the Journal focus on developments in addiction medicine as well as on treatment innovations and ethical, economic, forensic, and social topics including: •addiction and substance use in pregnancy •adolescent addiction and at-risk use •the drug-exposed neonate •pharmacology •all psychoactive substances relevant to addiction, including alcohol, nicotine, caffeine, marijuana, opioids, stimulants and other prescription and illicit substances •diagnosis •neuroimaging techniques •treatment of special populations •treatment, early intervention and prevention of alcohol and drug use disorders •methodological issues in addiction research •pain and addiction, prescription drug use disorder •co-occurring addiction, medical and psychiatric disorders •pathological gambling disorder, sexual and other behavioral addictions •pathophysiology of addiction •behavioral and pharmacological treatments •issues in graduate medical education •recovery •health services delivery •ethical, legal and liability issues in addiction medicine practice •drug testing •self- and mutual-help.
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